1. haidut

    Vitamin B3 counteracts (cancer) cachexia, by restoring NAD+ levels

    As many of my readers know, the majority of cancer patients do not succumb from the actual tumor burden, but as a result of (usually in that order) cachexia, immunocompromise from radiation/chemotherapy, hospital-acquired infection, and/or cytokine storm after surgery for removing the tumor. Of...
  2. haidut

    Muscle weakness / wasting linked to poor mitochondrial function

    A study that once again illustrates the central principle of bioenergetics - structure and function cannot be separated. They are interdependent at every level. In this specific case, the "structural" pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when...
  3. haidut

    Endotoxin Causes Cachexia In Cancer; How Statin Drugs Really Work

    The title of the post is a bit strange but it is pretty much what the study below found. Just like the SSRI drugs, the mechanism of action of statins is (officially) not really known. The official version for the antidepressant effects of SSRI drugs was that they increase intracellular levels of...
  4. haidut

    Cancer Is NOT Addicted To Glucose, As Previously Thought

    Little by little, the lies about cancer told for over 100 years start to fall apart. One of the last strongholds of the "traditional" view on cancer is that it is "addicted" to glucose and eating a high-carb diet fuels tumor growth. Evidence to the contrary has actually been available for...
  5. haidut

    Low DHT Levels May Be The Cause Of Wasting In HIV/AIDS

    While these studies only focus on the wasting syndrome in HIV/AIDS patients, the pathology of the wasting is virtually the same in other cachectic conditions including cancer, Cushing, sepsis, etc. If DHT does get approved by the FDA for muscle wasting, we may finally see a change in attitude in...
  6. haidut

    Cachexia Caused By Insulin Resistance

    The study was done with cancer but it probably applies to other conditions involving tissue wasting. Inability to burn sugar is what caused fat and muscle tissue to waste. This also matches Ray's views on why restricting glucose in cancer patients is pointless - i.e. the body will accelerate the...
  7. haidut

    Nsaid (aspirin) May Prevent Cancer Cachexia (wasting)

    Another study linking chronic inflammation to cancer and its signature muscle wasting condition known as cachexia. Yet another piece of the puzzle in how aspirin prevents and maybe even treats cancer. This study is also interesting b/c it found that that the current medical opinion vilifying fat...
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