brain

  1. P

    Metabolism Of Galactose In The Brain And Liver Of Rats And Its Conversion Into Glutamate And Other A

    Metabolism of galactose in the brain and liver of rats and its conversion into glutamate and other amino acids. - PubMed - NCBI Abstract Time- and dose-dependent measurements of metabolites of galactose (with glucose as control) in various organs of rats are discussed. Not only the liver but...
  2. haidut

    Blood Sugar Is Controlled Mostly By The Brain, Not Pancreas

    Ray wrote in one of his articles that pancreatic insulin is responsible for no more than 20% of glycemic control. While he mentioned potassium as the major factor, he also said that it is the brain that ultimately controls the levels of sugar in the blood. This study from Yale seems to confirm...
  3. haidut

    Why glucose oxidation is preferable to fatty acid oxidation

    I have seen this question come up many times on the forum. This study offers a potential answer and even though it focuses only on brain metabolism the given reasons are applicable for most other tissues as well. http://www.ncbi.nlm.nih.gov/pubmed/23921897 "...It is puzzling that hydrogen-rich...
  4. haidut

    Brain Levels Of Gaba Predict Tactile Learning Ability

    This study is perhaps counter-intuitive to some given that GABA is the major inhibitory neurotransmitter in the CNS. However, GABA has repeatedly been shown to be crucial for the ability of the brain to learn and cholinergic drugs that were tried for Alzheimers failed spectacularly. For those...
  5. L

    Caffeine And Effect On Brain Seen Through Scans

    Hmmm.... I know it is Daily Mail, but interesting: http://www.dailymail.co.uk/sciencetech/ ... =applenews
  6. P

    Brain PH And Lactic Acidosis: Quantitative Analysis Of Taurine Effect

    http://www.ncbi.nlm.nih.gov/pubmed/1336578 Abstract A quantitative analysis of taurine effect (facilitation of acid handling capacity of brain in response to anoxia/hypoxia by high levels of cytosolic taurine) was performed utilizing multinuclear (1H, 31P) in vivo nuclear magnetic resonance...
  7. haidut

    Running Marathons Shrinks The Brain

    Not that this is any surprise to the forum readers, but I found it quite alarming that the brain shrinks in a such a short amount of time even though the study claims that the brain recovers within 6 months after the event. What I found also interesting is the explanation for the shrinkage - the...
  8. P

    Role Of Low-Level Laser Therapy In Neurorehabilitation

    www.ncbi.nlm.nih.gov/pmc/articles/PMC3065857/ Abstract This year marks the 50th anniversary of the discovery of the laser. The development of lasers for medical use, which became known as low-level laser therapy (LLLT) or photobiomodulation, followed in 1967. In recent years, LLLT has become...
  9. J

    Glucocorticoids Cause Brain Damage

    For the last few years, studies on the use of glucocorticoids ( prednisone, dexamethasone,ect) resulted in a smaller hippocampus and prefrontal cortex. Causing memory loss, attention loss and lower concentration. This study shows that Prednisone can actually reduce brain weight and decrease...
  10. P

    The Effect Of Magnesium Sulfate On Cerebral Blood Flow Velocity, Cardiovascular Variables, And Arter

    http://www.ncbi.nlm.nih.gov/pubmed/10213436 Abstract Although there are data demonstrating reversal of cerebral vasospasm with magnesium sulfate, there is little information on the effects of magnesium on the normal intact cerebral vasculature. This study investigated the actions of magnesium...
  11. haidut

    Blocking Inflammation From PUFA Reverses Brain Aging

    This study is important on several levels. First, it shows that it is possible to fully reverse brain aging. Second, it suggests that one of the main mechanisms for brain aging is inflammation induced by the primary metabolites of PUFA - the leukotrienes. I talked about them in my first show...
  12. NathanK

    Fluorescent Light Kills Dopamine In The Brain

    Bright light exposure reduces TH-positive dopamine neurons: implications of light pollution in Parkinson's disease epidemiology http://www.ncbi.nlm.nih.gov/pubmed/23462874 Full text: http://digitalcommons.wustl.edu/open_access_pubs/1333/ The study used bright (fluorescent) light on surgically...
  13. N

    Different Brain Regions Are Infected With Fungi In Alzheimer’s Disease

    http://www.nature.com/articles/srep15015 Different brain regions including external frontal cortex, cerebellar hemisphere, entorhinal cortex/hippocampus and choroid plexus contain fungal material, which is absent in brain tissue from control individuals. Analysis of brain sections from ten...
  14. milk_lover

    According To A Study Done In 1988, Caffeine Can Increase Brain Serotonin Levels

    http://nutritionreviews.oxfordjournals. ... /46/10/366 I don't have an access to the full study. The abstract says the following: "High [d?]closes of caffeine produced increases in tryptophan and serotonin in brains of rats." Has anybody read the full study, checked if it was soundly designed...
  15. sweetly

    Near-infrared Light Is Neuroprotective In A Monkey Model Of Parkinson's Disease. (2015)

    http://www.ncbi.nlm.nih.gov/pubmed/26456231
  16. haidut

    Cyproheptadine Prevents Brain Damage From Stroke

    The effect was dose dependent and higher doses of cyproheptadine completely prevented the nervous system damage caused by stroke. Bufotenin, a type of serotonin, prevented the protective effects of cyproheptadine indicating that damage in stroke conditions is at least partially mediated by...
  17. haidut

    Glucose has the same effect on the brain as glycine

    Related to the other study on glucose I posted minutes ago. This study shows that just like glycine, taurine, and beta alanine glucose is a glycine "receptor" agonist. As such, it has an inhibitory effect on the brain and spinal cord and likely has similar effects to glycine on variety of...
  18. haidut

    Melatonin Elevates Brain Serotonin

    Ray has repeatedly warned against the exogenous supplementation with melatonin and has said that it is almost as dangerous as serotonin (of which melatonin is a metabolite). One of the main benefits of red light is that it sharply decreases melatonin synthesis, sometimes by as much as 90%. I...
  19. Demyze

    Pregnenolone And DHEA In Traumatic Brain Injury

    Today I heard the first mention of Pregnenolone outside of a "Ray Peat Source". Joe Rogan had a Dr. Mark Gordon on his podcast. Dr. Gordon is an endocrinologist who found that the levels of neurosteroids are very diminished in people who've experienced traumatic brain injuries. After a quick...
  20. haidut

    Carbs (not Meat) Were Crucial Factor For Developing Big Brains

    The Paleo community is ablaze as a result of this news article. The study claims that even though meat may have kickstarted the process of developing big brains, it was carbs that were crucial for the sustained development of a big brain and the intelligence associated with it. I think points 1)...
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