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bone

  1. haidut

    Cartilage/bone health depends on oxidative metabolism

    A good study that demonstrates yet another "structural" aspect of health - the strength and growth or our cartilage/bones - is heavily dependent on proper mitochondrial function. As such, even minor disruptions of oxidative metabolism can lead to long-term deformations in bone/cartilage, which...
  2. haidut

    Compared to meat eaters, vegans / vegetarian / pescatarians have higher risk of fractures

    The study just hit major news outlets and is generating a lot of "controversy". Why putting that word in quotes? Because, as I mentioned in several other posts, that word has become a euphemism for "embarrassing truth" that mainstream medicine (and often society at large) will do just about...
    • haidut
    • Thread
    • bone fracture malnourish pescatarian risk vegan vegetarian
    • Replies: 15
    • Forum: Scientific Studies
  3. Hans

    The Truth On DHT: What The Research Shows

    Hi all, There is a common misconception that DHT causes prostate cancer, hair loss and what else not. I've been sifting through the research on what the effects of high DHT actually is and what happens if men take large doses of DHT for long periods of time. Here are my findings: The truth on...
    • Hans
    • Thread
    • bone cardiovascular disease coronary artery disease dht hair loss insulin sensitivity metabolic syndrome muscle prostate cancer
    • Replies: 23
    • Forum: Articles & Scientific Studies
  4. Scott Andrew

    Ultrasound Therapy Device?

    Anybody have a good source for a personal Ultrasound Therapy Device? I have a minor bone bruise that I want to give one a shot on.
    • Scott Andrew
    • Thread
    • bone bone healing bruise calcium metabolism red light therapy ultrasound vitamin d
    • Replies: 0
    • Forum: Metabolism
  5. haidut

    Aspirin - A New Osteoporosis Drug

    A study published almost a decade ago made the bold claim that aspirin may be a novel drug for osteoporosis. [Effect of aspirin administration for the treatment of osteoporosis in ovariectomized rat model]. - PubMed - NCBI However, the study did not get much traction and was in fact mocked by...
    • haidut
    • Thread
    • aspirin bmd bone inflammation osteoporosis prostaglandins therapeutic treat
    • Replies: 12
    • Forum: Scientific Studies
  6. haidut

    Humans Have A 'salamander-like' Ability To Regrow Cartilage

    The title says it all, but the study authors make the unfortunate/handicapped conclusion that while we may very well be able to regrow cartilage, we cannot regrow limbs. Well, multiple animal studies I posted in the last beg to disagree and point to both high metabolism and progesterone as...
    • haidut
    • Thread
    • age bone cartilage children co2 humans limbs metabolism progesterone regenerate regrow salamander
    • Replies: 17
    • Forum: Scientific Studies
  7. A

    Osteocalcin, Not Adrenaline, Drives Fight Or Flight Response

    article of september 2019: Bone, not adrenaline, drives fight or flight response When faced with a predator or sudden danger, the heart rate goes up, breathing becomes more rapid, and fuel in the form of glucose is pumped throughout the body to prepare an animal to fight or flee. These...
    • alex mas
    • Thread
    • bone osteocalcin stress response
    • Replies: 27
    • Forum: Hormones
  8. haidut

    Osteoporosis Is Caused By Mitochondrial Dysfunction Driven By Nitric Oxide (NO)

    Let’s repeat the mantra one more time – structure and function cannot be separated, they are mutually dependent at every level of reality/life. As such, it is little surprise (to us) that a structural disorder like osteoporosis may be caused by a deficiency in energy production. Yet, despite...
    • haidut
    • Thread
    • bone breakdown cause cytochrome c cytochrome c oxidase damage dysfunction energetic inflammation metabolic mitochondria nitric oxide no osteoclasts osteoporosis rankl resorption stress
    • Replies: 10
    • Forum: Scientific Studies
  9. haidut

    Estrogen Is NOT Needed For Muscle / Bone Growth And Anabolism

    I have had my eye on posting this study for at least 3 years now but something more important always came up, so I kept putting it off. However, the recent thread posted on the forum about how estrogen is "essential" for health convinced me it is way overdue that I post something on this topic...
    • haidut
    • Thread
    • anabolic anabolism anastrozole aromatase inhibition bone bone growth bone health bone mineral density estrogen growth muscle muscle gain muscle mass testosterone trenbolone
    • Replies: 154
    • Forum: Scientific Studies
  10. haidut

    Pregnenolone Is Anabolic For Bones

    So much for pregnenolone being an inactive steroid. The study below shows that even very low concentrations of pregnenolone are high anabolic for the bone and its effects are comparable to those of potent steroids like DHT or the well-known androgenic-anabolic steroid (AAS) commonly known as...
    • haidut
    • Thread
    • alp anabolic androgens bone bones effects osteocalcin osteoporosis pregnenolone progestins
    • Replies: 15
    • Forum: Scientific Studies
  11. P

    Positive Effect Of Tetracycline Antibiotics On Bones

    Even subantimicrobical dose, improves bone quality . And apparently minocycline is the best tetracycline. But doxycycline is also interesting. Effects of tetracyclines on bones: an ambiguous question needs to be clarified. - PubMed - NCBI Effects of tetracyclines on bone metabolism. -...
  12. P

    Positive Effect Of H1 Antihistamines On Bone Density

    Anti-histamine Therapy and Bone Mineral Density: Analysis in a Population-Based U.S. Sample Background Histamine may play an important role in bone turnover. The data regarding histamine receptor antagonists (H1RA, H2RA) and bone mineral density in humans are sparse. We examined bone mineral...
  13. haidut

    Low DHEA-S Predicts Fractures In Older Men

    There is a big push to start treating older men with estrogen, just as women are, because estrogen is "good for the bone". No evidence exists to support this approach and in fact multiple studies in women have shown that low DHEA, and not estrogen, is what is associated with weak bones. In...
    • haidut
    • Thread
    • androgen bone deficiency dhea dhea-s fractures men older
    • Replies: 3
    • Forum: Scientific Studies
  14. haidut

    Fructose Is The Only Sugar Associated With Body Weight And Bone Health (in Infants)

    Another study suggesting fructose is probably not the villain we are led to believe it is, at least in infants. Fructose in Breast Milk Is Positively Associated with Infant Body Composition at 6 Months of Age "...Dietary sugars have been shown to promote excess adiposity among children and...
    • haidut
    • Thread
    • babies body composition bone bone health correlation fructose infants muscle mass positive weight
    • Replies: 16
    • Forum: Scientific Studies
  15. P

    Sucrose And Fructose Increase Adiponectin

    Metabolic stress with a high carbohydrate diet increases adiponectin levels. - PubMed - NCBI Abstract BACKGROUND: Adiponectin is an adipose tissue-specific protein, which possesses anti-atherogenic and antidiabetic properties, yet its plasma levels are decreased in subjects with metabolic...
  16. P

    Bone Regulates Glucose Metabolism As An Endocrine Organ Through Osteocalcin

    Bone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin. - PubMed - NCBI Skeleton was considered as a dynamic connective tissue, which was essential for mobility, calcium homeostasis, and hematopoietic niche. However more and more evidences indicate that skeleton works not...
    • paymanz
    • Thread
    • adiponectin beta cells bone diabetes fertility glucose metabolism osteocalcin sperm study testicular testosterone vitamin d vitamin k
    • Replies: 2
    • Forum: Scientific Studies
  17. haidut

    Vitamin K And D Reverse Muscle Aging, May Act Like Sports Doping Agents

    Vitamin D and K have a primary role in bone metabolism, together with calcium and the androgenic hormones. Ray has written about the importance of these vitamins not only for bone health but also for insulin sensitivity and accelerating deactivation of estrogen. Many of these beneficial effects...
    • haidut
    • Thread
    • aging bone cholecalciferol doping metabolism muscle osteocalcin vitamin d vitamin k vitamin k1 vitamin k2
    • Replies: 61
    • Forum: Scientific Studies
  18. P

    LRP5 Controls Bone Formation By Inhibiting Serotonin Synthesis In The Duodenum

    LRP5 - Wikipedia im so interest to find any info on how increase Lrp5(it strongly inhibit gut serotonin release) , only thing i found that upregulates the synthesis of it is vitamin D, and also Cholesterol. but who knows, maybe serotonin lowering effect of salt works through this pathway...
    • paymanz
    • Thread
    • antiserotonin bone curcumin inflammation jnk lrp5 obesity osteoarthritis osteoporosis serotonin serotonin depletion study vitamin d
    • Replies: 4
    • Forum: Articles & Scientific Studies
  19. haidut

    SSRI (Prozac) Drugs Cause Irreversible Bone Loss

    Ray has written about the detrimental effects of serotonin on bone health and how serotonin antagonist could be a potential treatment for osteoporosis. This study confirms Ray's points and shows that drug Prozac (and possible other SSRIs) causes irreversible bone loss. Selective Serotonin...
    • haidut
    • Thread
    • antagonist bone fluoxetine folate folic acid irreversible loss prozac serotonin ssri
    • Replies: 14
    • Forum: Scientific Studies
  20. P

    Pentoxifylline-tocopherol-clodronate Combination: A Novel Treatment For Osteoradionecrosis Of The Te

    Pentoxifylline-tocopherol-clodronate combination: A novel treatment for osteoradionecrosis of the temporal bone. - PubMed - NCBI Abstract BACKGROUND: Osteoradionecrosis (ORN) of the temporal bone is a complication of radiation therapy that is extremely challenging to manage. METHODS: We...
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