bipolar disorder

  1. haidut

    Inhibiting respiration/metabolism reliably causes bipolar disorder

    Just a quick post on a study, which claims to have established a reliable method for inducing bipolar disorder in an animal model. This reliable method consists simply of administering a low-dose of a mitochondrial inhibitor. More specifically, an inhibitor of complex I of the electron transport...
  2. haidut

    Chronic Stress / Defeat Causes Mental Illness By Damaging Mitochondria

    Yet another study demonstrating that mental illness has little to do with genetics, and is likely entirely due to energetic deficiency caused by environmental stress. This energetic deficiency is caused by mitochondrial damage caused by said stress. Keeping lipolysis and/or PUFA intake low can...
  3. haidut

    Serotonin Causes Bipolar Disorder (through Mitochondrial Dysfunction)

    Yet another nail in the coffin of the "happiness hormone", which may end up being one of the biggest scientific frauds of the 20th century, rivaling the one about estrogen being the "female" hormone. It has been known for a long time that both lithium and methylene blue, both of which are...
  4. haidut

    Bright Light May Treat Bipolar Disorder With The Same Response Rate As Lithium

    Bipolar disorder is one of the most difficult ones to treat and often requires hospitalization during episodes of acute mania. The god standard of treatment for this disorder is still lithium - a drug that has been in use for more than 100 years. This new study shows that simply getting...
  5. haidut

    High Lactate May Be The Cause Of Major Psychiatric Disorders

    The study itself has a misleading title because there are quite a few situations that can result in lower brain pH (and thus high acidity). High levels of CO2 can also cause low brain pH levels, but as I posted in a few other studies drugs that raise CO2 levels can actually treat mental disease...
  6. haidut

    Blocking Blue Light Can Cure Bipolar Disorder

    This is another great study for so many reasons. First, it adds to the evidence that bipolar disorder is probably environmental in origin, possibly linked to blue light pollution. Second, it adds to the evidence for a link between high cortisol / serotonin and bipolar disorder as blue light...
  7. haidut

    SSRI Can Lead To Public Health Disaster

    The article's focus is UK but the same argument applies to pretty much any Western country as the SSRI are a mainstream depression drug in most of the Western world. As you can see, these drugs are often the cause for the exact same problems they are supposed to treat. What's worse, once a...
  8. Dan Wich

    High-dose Methylene Blue For Treating Manic-depressive Psychosis

    A two-year double-blind crossover trial of the prophylactic effect of methylene blue in manic-depressive psychosis. - PubMed - NCBI (referenced in this study on methylene blue and depression)
  9. haidut

    Methylene Blue As A Treatment For Manic Depressive Psychosis

    The study was on bipolar disorder psychosis, which is different from the psychosis in conditions like schizophrenia. The psychosis of bipolar disorder is believed to be caused by cortisol, and since methylene blue helped then it suggests methylene blue can lower excessive cortisol. This is not...
  10. haidut

    Anti-serotonin, Pro-dopamine Drug Approved For Psychosis And Bipolar Disease

    After more than 5 decades of claiming that psychosis conditions like schizophrenia are caused by excessive dopaminergic activity and depression is a deficiency of serotonin, big pharma is doing 180 degrees reversal. A new drug was just approved for treating bipolar disorder and schizophrenia in...
  11. haidut

    A Selenium Compound May Treat Bipolar Disorder

    Back in the 1960s and 1970s there was a great interest in using selenium as a treatment for a number of inflammatory conditions, as well as damage caused by stroke and heart attacks. However, that enthusiasm was quickly dampened when the studies discovered that using high doses of selenium had...
  12. S

    Sodium, Lithium, Parkinson's

    Ray Peat has grouped Parkinson's disease with other effects of insufficient energy and calcium hyperexcitation. It can bee seen that lithium selects for healthier mitochondria: [http://www.raypeatforum.com/forum/viewtopic.php?f=36&t=4169&p=50330]. Lithium has many commonalities with sodium...
  13. haidut

    Pregnenolone May Treat Bipolar Depression

    Ray has said that depressed people taking pregnenolone recovered quickly and felt a "sense of resilience" when faced with depressive challenges. This was a human trial and dose was 500mg a day for 12 weeks. http://www.ncbi.nlm.nih.gov/pubmed/24917198 "...Depression remission rates were greater...
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