1. cs3000

    7,8-dihydroxyflavone (bdnf mimic) - Regenerates thymus, restores bone marrow activity, boosts hematopoietic stem cells, enhances bone strength

    As well as increasing neurogenesis (with antidepressent effect linked to increasing neuron number or myelination in the hippocampus) , BDNF has effects outside of the brain. as BDNF /TrkB expression is also found in decent amounts elsewhere in the body. e.g spleen, thymus bone marrow...
  2. cs3000

    Some info on nerve damage / ALS / multiple sclerosis / neurodegeneration / myelin disorders

    (oligodendrocytes & Schwann cells repair myelin and signal growth factors , but in ALS they are impaired) vitamin b5 (pantothenic acid) Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for...
  3. cs3000

    Silicon dioxide [common in supps] worsens neurogenesis in hippocampus. causes impairment in offspring. +Grape Seed Procyanidins Extract benefits

    The smaller nanoparticles specifically are dangerous. and no way of telling what you're getting with the silicon dioxide often found in supplements Maternal exposure to silicon dioxide nanoparticles reduces hippocampal neurogenesis and synaptogenesis and induces neurodegeneration in rat...
  4. cupofcoffee

    Coffee polyphenols ameliorate cognitive decline via maintenance of blood-brain barrier (BBB) integrity in senescence-accelerated mouse prone 8 (SAMP8)
  5. haidut

    Giving Niacinamide To Pregnant Females Greatly Benefits The Offspring

    A few very interesting studies came out in 2018 showing that niacinamide may be very helpful for (pre)-eclampsia, as well as prevent miscarriages and birth defects. Keep in mind that according to mainstream medicine, eclampsia is untreatable and the approach is to have the baby delivered ASAP...
  6. haidut

    Environmental Enrichment As Effective As Drugs For Treating Depression

    This study is really good because not only it states directly that depression can be directly caused by stress, but also because it shows that environmental enrichment (EE) for just 20 days can be at least as therapeutic as drugs. The beneficial effects of EE are well-known in psychiatry and...
  7. haidut

    Estrogen Impairs Memory In Women

    There has been some evidence from rodent studies that estrogen and BDNF are antagonistic to each other as animals exposed to estrogen cannot remember very well. BDNF is akin to an anabolic steroid for the brain, and estrogen powerfully impairs its effects, especially in cases of traumatic brain...
  8. haidut

    The Antidepressant Mechanism Of Androsterone

    There is solid evidence that androgens have potent antidepressant effects in both sexes. However, the mechanism of action of that antidepressant effect has not been fully elucidated yet. On the other hand, it is also well known that chemicals that increase the levels of the so-called...
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