aspirin

  1. haidut

    Aspirin protects the liver from paracetamol

    As many of you know paracetamol is very toxic to the liver and the mechanism of action is rapid depletion of glutathione (GSH). This study shows that aspirin protected the liver from GSH depletion induced by paracetamol. So, the next time your doctor tells you that aspirin is bad for the liver...
  2. S

    Aspirin for insulin resistance while low-carbing

    Hi everyone, I am new to the Ray Peat "system," and I am very interested in some aspects of the approach. I found the forum while researching thyroid glandular supplements, and as I began browsing, I came across many new concepts and supplements. One thing in particular about which I would be...
  3. haidut

    Aspirin Reduces Death / Complications From GI Bleeding

    Aspirin is commonly bashed by modern medicine as a somewhat useful drug that is severely handicapped by its side effects such as bleeding in the GI tract or brain. Well, guess what - aspirin actually protects against mortality and complications caused by GI bleeding. On the other hand, common...
  4. S

    Aspirin Crystals

    Does anyone know about aspirin powder? The "crystals" Ray Peat talks about? I'm looking to buy some but I don't know what brand to get.
  5. N

    High levels of prostoglandins suppress testosterone production - try Aspirin?

    http://scholarworks.wmich.edu/honors_theses/168/ Ray suggests a number of poor health states can increase prostoglandins. It looks like over a certain level they suppress T production directly - in the leydig cells of the testes. We already know from Peat that prostoglandins increase...
  6. haidut

    Aspirin Reduces Ammonia?

    I posted some threads on sodium benzoate being sold as a drug in the USA for reducing ammonia. Ceylon cinnamon metabolized into sodium benzoate and has been shown in a number of animal studies to reduce ammonia concentrations in brain and plasma. The mechanism of action is bezoic acid forming a...
  7. haidut

    Aspirin Comparable To DNP As Mitochondrial Uncoupler

    This image is from the study I posted on the effects of aspirin on GI tract. As you can see from the attached image, aspirin increased mitochondrial respiration by 300% while DNP increased it by 400%. However, the authors stated that this concentration of DNP is not safe and in reality most...
  8. haidut

    Aspirin Does NOT Cause Damage To Stomach Or Intestines

    There has been a great deal of controversy in regards to the effects of aspirin on the GI tract. Most sources of "common" medical knowledge claim that aspirin is very bad for the GI tract, while Ray has claimed that is not true and sometimes even the opposite. This study claims that aspirin...
  9. haidut

    Topical Absorption Of Caffeine, Aspirin And Niacinamide

    Another study, which looked at absorption of these Peat-approved substances through human skin. http://www.nature.com/jid/journal/v54/n ... 18185a.pdf Niacinamide absorption in acetone (the solvent used in the study) was only about 10%, however as per another human study I posted some time...
  10. burtlancast

    Taking Willow Bark Extracts Instead Of Aspirin ?

    I've heard Willow Bark ( from which non synthetic aspirin is extracted) has a longer lasting effect than aspirin, and much lower dangers of gastro-intestinal bleeding. Has Ray discussed this alternative to aspirin ?
  11. cantstoppeating

    Acetylsalicylic Acid (aka Aspirin) Vs pure Salicylic Acid

    I have the opportunity to purchase pharmaceutical grade Salicylic Acid and would like to know if its difference from regular aspirin (i.e. acetylsalicylic acid) matters when taking it for Peat-purposes. A google search reveals people stating it's not the same but there isn't any more...
  12. haidut

    Moderate Doses Of Aspirin Reverse Insulin Resistance

    The study was in rats but it has been replicated in humans as well, even though the replication study in humans used much higher doses of aspirin (human dose 90mg/kg). This study used smaller doses of aspirin equivalent to 650mg taken every 6 hours. If this works, it could be a much safer dosing...
  13. I

    How To Get Over Aspirin Allergy

    Looking for suggestions on how to tackle my aspirin allergy. The last time I took 2 aspirin (pill format, without dissolving) I had a severe allergy attack of sneezing/runny nose that lasted for hours. After that I tried dissolving it in water and not consuming the settled bits, but it still...
  14. S

    Prostaglandin Could Cause Up To 40% Of Preterm Births

    Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane
  15. haidut

    Biggest Study So Far Shows Aspirin Reduces Any Cancer Risk

    Nothing new, but the evidence from larger and larger trials continues to pile on. Unfortunately, these are all observational studies and focus on prevention and mortality. I don't know of any large trials for treating cancer with aspirin, and the few small ones that exist use very low dosages...
  16. haidut

    Negative effects of aspirin may be due to glycine depletion

    Some people have trouble taking aspirin even in small doses. Most often they get symptoms like tinnitus, GI discomfort, nervous system overexcitement, etc. It just happens that glycine (and also taurine) happen to help with all of these symptoms. So, I did some digging and it looks like aspirin...
  17. haidut

    Taurine Enhances Aspirin Absorption

    Given how similar taurine is structurally to glycine, this is not surprising but I wanted to post it anyways as an extra option for people who do not have access to glycine powder/tablets but have taurine. http://www.ncbi.nlm.nih.gov/pubmed/7277191 "...Aspirin absorption from the stomach or...
  18. haidut

    Glycine Virtually Eliminates Adverse GI Effects Of Aspirin

    I posted a study earlier on co-administration of glycine improving the absorption of aspirin. It looks like it also prevents the negative GI symptoms of aspirin intake in some people. The ratio needed is 2:1 in favor of aspirin, which means that if you are taking 1g of aspirin, you need to take...
  19. H

    Aspirin And Muscle Repair?

    Hello, sorry if this was already answered; I can't find much info on this: I'm trying to bulk up a bit and I'd like to take aspirin to inhibit aromatase but weight lifters advise against drugs that inhibit protein synthesis/the inflammatory responses necessary for muscle growth. I've read that...
  20. BingDing

    Michael Crichton on aspirin

    When Crichton was in med school he published several books under the pseudonym of Jeffery Hudson. Whatever the name, all his books are full of factoids. "A Case of Need" is a whodunit in a medical setting. Talking about post WWII medicine, he says that by 1965 three of the four most commonly...
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