aromatase

  1. haidut

    Low-dose DHEA Inhibits Aromatase By 35% And Endotoxin Blocks That Effect

    I found this study while researching the conversion of DHEA into steroids with immunomodulating effects. As you can see (attached picture), a DHEA concentration of 1µM inhibited aromatase activity by about 35%. This concentration of DHEA can be easily achieved with 3mg - 5mg topical DHEA in...
  2. P

    Aromatase Inhibition Significanty Enhance Nerve Regeneration

    Sex differences in the effectiveness of treadmill training in enhancing axon regeneration in injured peripheral nerves. - PubMed - NCBI Exercise in the form of daily treadmill training results in significant enhancement of axon regeneration following peripheral nerve injury. Because androgens...
  3. haidut

    Estrogen Causes Epilepsy/seizures; Aromatase Inhibitors Are Viable Treatment

    In perhaps what is one of the most striking and open confirmations of Ray's views, this study finally acknowledges what the man has been saying for years. Estrogen is a major cause (and maybe even THE cause) of epilepsy and its associated seizures, and inhibiting estrogen synthesis may be a...
    • haidut
    • Thread
    • aromatase epilepsy estrogen inhibitor seizures treatment
    • Replies: 16
    • Forum: Scientific Studies
  4. P

    Aromatase Inhibitors Regenerate The Thymus In Aging Male Rats

    http://www.ncbi.nlm.nih.gov/pubmed/1521922 Abstract The thymus can be regenerated in aging rats by surgical or chemical castration and regeneration is inhibited by testosterone, which may exert this effect, at least in part, through its conversion to estradiol. An attempt has been made to...
  5. Dan W

    Coffee And Cocoa As Aromatase Inhibitors

    I had to post this because we've gone nearly 17 minutes without discussing an aromatase inhibitor :lol: I don't have access to the full text of this study, but it's referenced elsewhere as showing coffee and cocoa strongly inhibiting aromatase in a microsomal assay...
  6. haidut

    Methylene Blue (MB) Is A Potent Aromatase Inhibitor

    I can't find the original reference on PubMed or anywhere else, so if someone can dig that up for me I'd really appreciate it. For now, we'll have to accept the following statement from the book (the book seems rather legit btw). https://books.google.com/books?id=plBoB ... se&f=false...
  7. haidut

    Chronic Ethanol Consumption Same As Chemical Castration

    As Ray said, alcohol is estrogenic and should be consumed in moderation and preferably using clear spirits. The fact that castration and chronic alcohol consumption did not have synergistic effects suggests that alcohol consumption alone matched the effect of castration. Effects of chronic...
  8. haidut

    Noradrenaline (and Likely Adrenalin) Increases Estrogen

    The mechanism is through activation of aromatase. Note the double hit - i.e. noradrenalin both increased the synthesis of estrogen through aromatase AND also decreased DHT synthesis through 5-AR. http://www.ncbi.nlm.nih.gov/pubmed/6290295 "...NE (10 microM) added to pineal organ cultures...
  9. haidut

    Pregnenolone, Progesterone And Androsterone Are Aromatase Inhibitors

    I have seen some people in the forum claim that they thought pregnenolone increased their estrogen levels. According to this study, pregnenolone should in fact lower estrogen by inhibiting aromatase. Peat has already written extensively on progesterone being a known aromatase inhibitor, so that...
    • haidut
    • Thread
    • androsterone aromatase aromatase inhibition dht inhibitor pregnenolone progesterone
    • Replies: 125
    • Forum: Scientific Studies
  10. haidut

    Selenium Is Anti-estrogenic (aromatase Inhibitor)

    Another confirmation that most of the substances favored by Peat have anti-estrogenic action even if he did not directly state it. http://www.ncbi.nlm.nih.gov/pubmed/22128327
  11. haidut

    Vitamin A (retinol) Inhibits Aromatase

    I mentioned this in my other posts but wanted to post at least one direct study for those interested in the vitamin A anti estrogenic effect: Retinol inhibits aromatase activity and expression in vitro. - PubMed - NCBI "...Aromatase converts androgens into estrogens and is thought to supply a...
    • haidut
    • Thread
    • aromatase aromatase inhibition estrogen study vitamin a
    • Replies: 2
    • Forum: Scientific Studies
  12. haidut

    Vitamin E (tocopherol) Is A Potent Aromatase Inhibitor

    Hi all, As you know Ray has written extensively on the benefits of Vitamin E though its actions as an estrogen antagonist. I opsted some studies that show that tocopherols act directly like estrogen "receptor" antagonist and this may explain some of their anti-estrogenic properties. However...
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