aromatase inhibition

  1. haidut

    Estrogen Is NOT Needed For Muscle / Bone Growth And Anabolism

    I have had my eye on posting this study for at least 3 years now but something more important always came up, so I kept putting it off. However, the recent thread posted on the forum about how estrogen is "essential" for health convinced me it is way overdue that I post something on this topic...
  2. haidut

    Pregnenolone Is As Potent As Progesterone As An (irreversible) Aromatase Inhibitor

    Progesterone does not need an introduction here and most people are likely aware of its antiestrogenic effects. A few years ago, I posted a thread with an old French study showing that a 500mg daily dose pregnenolone completely blocked estrogen's effects - an effect identical to what...
  3. Lokzo

    Calcium Deficiency Increases Aromatase And Subsequent Estrogen In Male Rats

    A calcium-deficient diet caused decreased bone mineral density and secondary elevation of estrogen in aged male rats-effect of menatetrenone and elcatonin. @haidut You will like this :)
  4. haidut

    Reducing Estrogen Synthesis Regenerates Thymus Destroyed By Aging

    Recently, I posted a thread showing that immune dysfunction (thymus shrinkage) which developed with aging (and excess of PUFA, estrogen, cortisol) explains cancer incidence much better than any genetic model. Immune Dysfunction (cortisol/estrogen/PUFA), Not Genetics, Causes Cancer The quote...
  5. haidut

    Gonadin - Liquid Steroid Optimizer For Lab/R&D

    EDIT (11/1/2021): New version of Gonadin (called it Gonadin+ on one recent podcast with Danny Roddy, but I decided to keep the name as just Gonadin) has been released on November 1, 2021. The description of the ingredients that have been removed, and the studies about them, can be found in the...
  6. haidut

    Androsterone - A Potent Steroidal Aromatase Inhibitor

    It is well-known in medical circles (at least in doctors over 50) that some androgens like DHT are potent aromatase inhibitors (AI). In fact, before the advent of modern AI drugs like letrozole, anastrozole and fadrozole the 5-AR androgens were a mainstream therapy for estrogen-receptor-positive...
  7. haidut

    Androgen Treatment Highly Effective For Breast Cancer

    The first study (animal) looked at various approaches and found that removal of the pituitary caused the complete disappearance of breast cancer in ALL of the studied animals. The administration of DHT caused almost complete regression in 82% (14 out of 17) of the animals. The HED for DHT was...
  8. P

    Aromatase Inhibition Significanty Enhance Nerve Regeneration

    Sex differences in the effectiveness of treadmill training in enhancing axon regeneration in injured peripheral nerves. - PubMed - NCBI Exercise in the form of daily treadmill training results in significant enhancement of axon regeneration following peripheral nerve injury. Because androgens...
  9. P

    Aromatase Inhibitors Regenerate The Thymus In Aging Male Rats Abstract The thymus can be regenerated in aging rats by surgical or chemical castration and regeneration is inhibited by testosterone, which may exert this effect, at least in part, through its conversion to estradiol. An attempt has been made to...
  10. C

    Ornithine And Aromatase Inhibition

    Hi, I was reading about the effectiveness of various 'aromatase inhibitors' - particularly those 'natural' compounds found in supplements derived from extracts of plants (ie. grape fruit extract, curcumin, blueberries, celery, fenugreek, ginger, goji, safflower, etc). In my reading, I have...
  11. YuraCZ

    Aromatase Inhibitors

    [moderator edit: posts moved from Caffeine is a potent anti-estrogen; can block estrogen "receptor" completely] Bodybuilders have a really simple solution for estrogen. They simply take Why Peat don't recomend this drug and overthinking this...
  12. natedawggh

    Is Horseradish An Aromatase Inhibitor?

    I have experienced a highly thermogenic effect consuming shrimp, but I also wanted to investigate the cocktail sauce I so liberally consumed them with. I read that horseradish is an aromatase inhibitor, but I can't find any studies or proof of action. Does anyone know about this? Has anyone used...
  13. haidut

    Pregnenolone, Progesterone And Androsterone Are Aromatase Inhibitors

    I have seen some people in the forum claim that they thought pregnenolone increased their estrogen levels. According to this study, pregnenolone should in fact lower estrogen by inhibiting aromatase. Peat has already written extensively on progesterone being a known aromatase inhibitor, so that...
  14. haidut

    Vitamin A (retinol) Inhibits Aromatase

    I mentioned this in my other posts but wanted to post at least one direct study for those interested in the vitamin A anti estrogenic effect: Retinol inhibits aromatase activity and expression in vitro. - PubMed - NCBI "...Aromatase converts androgens into estrogens and is thought to supply a...