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  1. F

    Serotonin too LOW due to antihistamines for long periods?

    Hi guys, I was wondering if continuous antihistamine usage (I'm cycling Zyrtec and Ebastine) could theoretically cause serotonin to drop too low. I know that this forum "hates" serotonin, but lately I'm dealing with anxiety, overthinking, worrying and also some mild OCD symptoms - could these...
  2. Lynne

    Existing antihistamine drugs show effectiveness against COVID-19 virus in cell testing

    Benadryl, etc may be effective in treating COVID-19. Surprise, surprise! Did you see this one @haidut? Sorry if there's a better category for this thread, or if it's already been posted, but I couldn't find it mentioned anywhere...
  3. ScurveDream

    Chronic Pain Relieved Greatly By Benadryl/diphenhydramine & Nightmares (story-time)?

    I'm including details here that I've never told anyone/written that much about to my knowledge, but all of it does not need to be read if you're not used to my extremely long, often (arguably) strange posts I make here. So I was going to post here about it (the pain), but figured it would be a...
  4. Hugh Johnson

    Lidocaine Demethylates DNA

    Lidocaine time- and dose-dependently demethylates deoxyribonucleic acid in breast cancer cell lines in vitro http://bja.oxfordjournals.org/content/early/2012/04/26/bja.aes128.full I wonder if chronic oral intake could reverse gene methylation.
  5. haidut

    Theanine Is An Antihistamine

    In addition to its anti-serotonergic properties, theanine appears to lower histamine release and act as a mast cells stabilizer. Drugs that act as mast cell stabilizers, for instance Ketotifen, and currently one of the most promising agents for treating gut conditions like IBS and Chron's. Most...
  6. R

    Should Peatarians Consider Antihistamines?

    In several of his articles, Ray Peat suggests or implies that anthistamines may have beneficial effects. A few examples follow. (From "Serotonin, Depression, and Aggression: The Problem of Brain Energy.") (From "Not the 'Female Hormone,' But the Shock Hormone.") (From "Oils in Context.")...