1. haidut

    5α-DHP - Liquid 5α-Dihydroprogesterone For Lab/R&D

    ****DISCONTINUED****DISCONTINUED****DISCONTINUED**** Replaced by allopregnanolone, which is a direct metabolite of 5α-Dihydroprogesterone (5α-DHP).
  2. haidut

    5α-Dihydroprogesterone (5α-DHP) - The Primary Progestogen Neurosteroid

    It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
  3. haidut

    Androsterone - Liquid Androsterone For Lab/R&D

    EDIT: Since I keep getting questions about androsterone, here is Ray's response when asked about it: Ray Peat Email Advice Depository Discussion/Comment Thread "...I think it would be safe enough to try in treating cancer or brain degenerative diseases." Here is one reference that gives backing...
  4. haidut

    Caffeine Is A Potent Anti-estrogen; Can Block Estrogen "receptor" Completely

    After reading the study on caffeine and breast cancer I posted in a different thread, I found some facts that U thought warranted a separate thread. Here is the original thread. viewtopic.php?f=75&t=6481 It looks like caffeine has such a potent anti-estrogenic activity that it is capable of...
  5. haidut

    Vitamin A Is Anti-Estrogenic

    Unlike all the other studies I have seen this is an in vivo study, so it provides some guidelines on dosage. The human equivalent dosage would be in the range of 200,000 - 250,000 IU of all-trans-retinoic acid (which is a metabolite of retinol). That is on the high end, but note that the...
  6. haidut

    Selenium Is Anti-estrogenic (aromatase Inhibitor)

    Another confirmation that most of the substances favored by Peat have anti-estrogenic action even if he did not directly state it.