1. haidut

    5α-DHP - Liquid 5α-Dihydroprogesterone For Lab/R&D

    As many of you know by now, I have acquired an interest lately to research the connection between the process of saturation of various nutrients and steroids and the effects of this saturation on the properties of these substances. After doing some work on androgens such as androsterone and...
  2. haidut

    5α-Dihydroprogesterone (5α-DHP) - The Primary Progestogen Neurosteroid

    It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
  3. haidut

    Androsterone - Liquid Androsterone For Lab/R&D

    EDIT: Since I keep getting questions about androsterone, here is Ray's response when asked about it: Ray Peat Email Advice Depository Discussion/Comment Thread "...I think it would be safe enough to try in treating cancer or brain degenerative diseases." Here is one reference that gives backing...
  4. haidut

    Caffeine Is A Potent Anti-estrogen; Can Block Estrogen "receptor" Completely

    After reading the study on caffeine and breast cancer I posted in a different thread, I found some facts that U thought warranted a separate thread. Here is the original thread. viewtopic.php?f=75&t=6481 It looks like caffeine has such a potent anti-estrogenic activity that it is capable of...
  5. haidut

    Vitamin A Is Anti-Estrogenic

    Unlike all the other studies I have seen this is an in vivo study, so it provides some guidelines on dosage. The human equivalent dosage would be in the range of 200,000 - 250,000 IU of all-trans-retinoic acid (which is a metabolite of retinol). That is on the high end, but note that the...
  6. haidut

    Selenium Is Anti-estrogenic (aromatase Inhibitor)

    Another confirmation that most of the substances favored by Peat have anti-estrogenic action even if he did not directly state it.