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EDIT (11/1/2021): New version of Gonadin (called it Gonadin+ on one recent podcast with Danny Roddy, but I decided to keep the name as just Gonadin) has been released on November 1, 2021. The description of the ingredients that have been removed, and the studies about them, can be found in the...
I just posted a thread about androsterone and its potent anti-depressant effects:
Androsterone - An Andidepressant Neurosteroid
Just like allopregannolone (ALLO), androsterone is 5-AR derived neurosteroid, and just like allopreganolone androsterone is a very potent GABA agonist (even more...
The study used the activated form of B6 (pyridoxal-5-phosphate, P5P) and the human equivalent dosage was 500mg-600mg. The mechanism of action was the reduction of brain levels of glutamate via activation of glutamate dehydrogenase (GDH).