antagonist

  1. haidut

    The Serotonin Receptor 5-HT2B Is Required For Cancer; Can Be Blocked

    I think this study should be sent to every pharma executive and brainwashed whitecoat who claims that serotonin is a good hormone promoting happiness and health. Actually, pharma companies have no illusions and know very well what's going on. Hence, the recent acquisition of Pfizer to the...
  2. haidut

    Fluoride In Tap Water Could Be A Causative Factor In Diabetes

    While the public health authorities continue their mantra on the "benefits" of fluoride for teeth and bone health, there are quite a few research groups that have been producing solid evidence to the contrary. As many of you know, fluoride is a proven thyroid inhibitor. As such, it is expected...
  3. haidut

    Vitamin A (retinol) Is Endotoxin (LPS / TLR4) Antagonist

    Another one in the series of endotoxin antagonism featuring so far vitamins D and B2. Vitamin B2 (riboflavin) Is Endotoxin Antagonist Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked...
  4. haidut

    Vitamin B2 (riboflavin) Is Endotoxin (LPS / TLR4) Antagonist

    This is just a follow up on the recent post on both riboflavin and vitamin D. Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections https://raypeatforum.com/community/threads/vitamin-d-is-endotoxin-lps-tlr4-antagonist-may-treat-lps-linked-conditions.12060/...
  5. haidut

    Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked Conditions

    The activation of TLR by various substances like endotoxin, ethanol / alcohol, opioids, SSRI, etc is involved in the pathogenesis of many conditions, especially IBD, colon cancer, periodontal disease, etc. There are very few effective endotoxin antagonists in clinical use, which is unfortunate...
  6. haidut

    Cyproheptadine Is An Estrogen Antagonist, May Treat Breast Cancer

    Ray wrote in some of his articles that estrogen mediates its effects through histamine and the cholinergic system, so anti-histamines and anti-cholinergic drugs can block estrogen's effects. Well, cyproheptadine is both an anti-histamine and an anti-cholinergic so it is not surprising to find...
  7. haidut

    Harvard Creates Batteries Using Quinones And Riboflavin

    I am posting this simply because I thought it is a cool study that illustrates the electrical versatility of electron withdrawing agents like the quinones, riboflavin, and even NAD. Harvard's battery tech takes cues from vitamin B2 "...A team of Harvard scientists on a quest to find an organic...
  8. haidut

    Serotonin As The Cause Of Acute Pancreatitis

    As some of you know, pancreatitis is a condition very common among alcoholics and people on SSRI drugs. When it is acute it can be quite deadly and its incidence has been skyrocketing lately, which concided with rising rates of alcohol abuse among middle-class citizens in the Western world. The...
  9. haidut

    Acute Colon / Lung Damage May Be Due To Endotoxin; Breast Milk Stops It

    The study was done to mimic the condition necrotizing enterocolitis in premature babies, but if you look at the actual study the scientists think the mechanism is probably the same for most cases of acute colon and lung damage. Once again, our old "friend" endotoxin rears its ugly head and acts...
  10. haidut

    Ritanserin - Serotonin Antagonist For R&D Use Only

    As promised, I finally got around to releasing the unicorn of the anti-serotonin world - i.e. the chemical known as ritanserin. It does not have a trade name as it is a research/lab chemical only and was never submitted for approval by the FDA. However, research with ritanserin is thriving and...
  11. haidut

    Caffeine Is A Serotonin Receptor Antagonist

    I was thinking about this recently in light of the strong evidence that caffeine is effective in preventing and even reversing liver fibrosis. It's Official - Caffeine Prevents And Slow Liver Fibrosis / Cirrhosis, Cancers I have posted a number of studies showing that serotonin and especially...
  12. haidut

    RoundUp (Glyphosate) Finally Proven Toxic - It Depletes Glycine

    For more than 2 decades Monsanto has been denying that RoundUp has a provable adverse effects on living organisms. The official reason cited was that there was no known mechanism through which glyphosate (active ingredient in RoundUp) can exert detrimental effects on the cell. Sounds...
  13. haidut

    An Anti-serotonin, Pro-dopamine Drugs May Treat Systemic Sclerosis

    Big Pharma is slowly prepping us for the inevitable admission that serotonin is really not that good for us. Of course, it will not happen publicly but through the approval of drugs that block serotonin and promote dopamine activity. This news piece shows that the drug terguride (a lisuride...
  14. haidut

    Enlarged Prostate (BPH) Can Be Treated By Anti-adrenaline Drugs

    Adding to the long list of conditions caused by high levels of stress hormones and overactivation of the sympathetic nervous system (SNS), BPH now joins that list. Given that BPH is a conditions predominantly found in older males, its pathology is not surprising given the chronic elevation of...
  15. haidut

    Serotonin Antagonists As Therapy For Alzheimer Disease

    As I posted in another thread, over 90% of the drugs tested for Alzheimer during the last 10 years have veen utter and abject failure. This is a pretty solid indication that the theory of Alzheimer's pathology and proposed beneficial pathways on which these drugs were based is solidly wrong...
  16. haidut

    SSRI (Prozac) Drugs Cause Irreversible Bone Loss

    Ray has written about the detrimental effects of serotonin on bone health and how serotonin antagonist could be a potential treatment for osteoporosis. This study confirms Ray's points and shows that drug Prozac (and possible other SSRIs) causes irreversible bone loss. Selective Serotonin...
  17. haidut

    Pregnenolone Is An Estrogen Antagonist

    This has been stated by Peat a few times but usually the assumption has been that pregnenolone converts into progesterone and that is how it exerts its anti-estrogenic effects. This older study claims that pregnenolone (also called delta-5-pregnenolone) is directly antagonistic to estrogen...
  18. haidut

    DHT Is Estrogen "receptor" Antagonist

    I have posted studies on DHT inhibiting aromatase and increaseing estrogen conjugation and excretion by the liver. However, this study shows that DHT is actually capable of direct anti-estrogen activity by binding to and antagonizing the estrogen "receptor" similarly to progesterone and vitamin...
  19. haidut

    DHT Reduces Glucocorticoid Effects

    I mentioned this on one of the Danny Roddy shows, but wanted to post this study here as many people have been asking me for references over email. In addition to reducing glucocorticoid effects, DHT is also an estrogen "receptor" antagonist as I posted in another thread. DHT Is Estrogen...
  20. haidut

    Male Fertility Requires Progesterone And Antagonism Of A PUFA Metabolite

    Ray has written many times on progesterone's role in both female and male health. This study discovered that sperm actually has a progesterone "receptor" on its tail, and it is the activation of this "receptor" by progesterone that allows sperm to make the final push into the egg and perform the...
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