androgens

  1. Mauritio

    Long term DHEA supplementation doubles androgens and progesterone in males

    I'm not sure if this study has been posted before , at least I haven found anything under the "DHEA" tag. Anyways, it's always good to have more in vivo evidence for peaty substances and what they do in real life. This study gave aging men with partial androgen deficiency (58-69)the "low dose"...
  2. S

    My Experiences With Raising Androgens Log (Pansterone, k2, magnoil)

    So for the past week I have been applying 1 dose (4 drops) of Pansterone (sfa, anhydrol) alongside 2-4 drops of Kuinone (every 2 days) to the scrotum in hopes of raising androgens and thus libido and sexual function. Positives since starting: - Occasional morning wood (although not 100%) -...
  3. cupofcoffee

    Dr. Shanna Swan on How Plastics in Food are Affecting Our Hormone Levels

  4. cupofcoffee

    Trenbolone Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    https://academic.oup.com/endo/article/157/1/368/2251856 perhaps this shows how non-aromatizable steroids can be more beneficial than testosterone in certain subjects. What do you think @haidut? is trenbolone peaty? /s
  5. Lokzo

    Daily Intake Of Alfalfa Sprouts, But Not Broccoli Sprouts, Increase DHT Levels

    Objectives: Dihydrotestosterone (DHT) is known as the main cause of androgenetic alopecia (AGA). We previously reported that sulforaphane (SFN), a compound extracted from broccoli, promotes hair regeneration in ob/ob mice by lowering plasma DHT levels. The aim of this study was to assess whether...
  6. Sefton10

    Androgens For Castrated Dog?

    Our dachshund (now 4 and a half) was castrated pretty early as a pup. One of his testicles hadn't descended properly and we were advised by the vet to get it done as there was a risk of cancer the longer it was left. I know now this was probably an error and we should have gotten a second...
  7. haidut

    Cholesterol And SFA Are Anabolic; PUFA/MUFA Akin To Chemical Castration

    A pair of interesting study and a commentary in the highly respected Journals of Gerontology. Namely, higher cholesterol intake is associated with much higher lean muscle mass accrual as a result of weight lifting. Interestingly, higher protein intake was not. Even more interestingly, and much...
  8. haidut

    Pregnenolone Is Anabolic For Bones

    So much for pregnenolone being an inactive steroid. The study below shows that even very low concentrations of pregnenolone are high anabolic for the bone and its effects are comparable to those of potent steroids like DHT or the well-known androgenic-anabolic steroid (AAS) commonly known as...
  9. haidut

    The Progesterone-like Action Of Testosterone And Other Androgens

    I am posting this simply as a response to the many hateful comments I got in regards to my discussion of testosterone as a progestin. Peat also alluded to the fact that testosterone has activity on the progesterone receptor and is likely safer as a "progestin" than the synthetic progestins being...
  10. haidut

    Acetaminophen (Tylenol) Depletes DHEA-S And Other Sulfated Steroids

    It is well-known that in animal studies acetaminophen has a potent anti-androgenic and feminizing effect. In some animal models it also reliably causes autism-like symptoms. Given its widespread use and heavy marketing by hospitals, especially to pregnant women (due to its lack of effect on...
  11. haidut

    Low DHT Levels May Be The Cause Of Wasting In HIV/AIDS

    While these studies only focus on the wasting syndrome in HIV/AIDS patients, the pathology of the wasting is virtually the same in other cachectic conditions including cancer, Cushing, sepsis, etc. If DHT does get approved by the FDA for muscle wasting, we may finally see a change in attitude in...
  12. haidut

    Calcirol - Liquid Vitamin D3

    Just like the other vitamin products we have released, this product does not really need any introduction to anybody familiar with Peat's work. So, unlike other products of ours, there won't be as many references listed in support of this product but I think even the few ones below are enough to...
  13. AretnaP

    If You Don't Want Low Testosterone DO NOT FAST

    There is a particular user on this forum who had been proposing fasting as a way of "resetting the receptors". The idea of course being that if you have low levels of a hormone you will experience an increased number of the proteins that the hormone interacts with. I am highly skeptical of this...
  14. haidut

    PUFA And MUFA Are Strong Inhibitors Of 5-AR, Saturated Fatty Acids Are Not

    I have posted quite a few studies showing the effects of various fatty acids on estrogen, androgen and glucocorticoid synthesis. This study shows that both PUFA and MUFA are strong inhbitors of 5-AR, with PUFA being the more potent inhibitors and inhibition potency being strongly dependent on...
  15. haidut

    A List Of Androgens That Stimulate 5-AR Activity

    Increasing 5-AR activity has received a lot of interest lately due to its therapeutic effects on mood disorders as well as issues with excess cortisol (5-AR deactivates cortisol). Unfortunately, the official story is that there are no freely available compounds that can stimulate 5-AR activity...
  16. haidut

    Androgens (androsterone/DHEA/T) Are Calcium Channel Blockers / Antagonists

    The study found that all tested androgens, as well as progesterone were calcium channel blockers and 5b-DHT was the most potent. Androsterons was next, and it was equipotent to DHEA and testosterone. While the dose used in the study was high, the authors believe that the same effects may be...
  17. haidut

    The Thyromimetic Mechanism Of Androsterone (and Other Androgens)

    As I posted in one of the androsterone threads, studies in the first half of the 20th century discovered hypocholesteremic and pyrogenic effects of androsterone and many animal models and also in humans. However, the direct mechanism for these effects of androsterone was not elucidated by these...
  18. Drareg

    SHBG Gene Promoter Polymorphisms In Men Are Associated With Serum Sex Hormone-binding Globulin, Andr

    This interesting in relation to the femur bone growth. SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density. Abstract CONTEXT: SHBG regulates free sex steroid levels, which in...
  19. Drareg

    SHBG, Plasma, And Urinary Androgens In Weight Lifters After A Strength Training

    "Previous studies with different results have suggested that total and bioavailable testosterone levels are modified by physical exercise. Such changes may be related to modifications in cortisol levels and could be reflected in some urine androgens. To determine how weight lifting training may...
  20. haidut

    Raising Serum Androgens Using DHEA, Pregnenolone, And Vitamin K

    User testimony (4/26/2021): My Experiences With Raising Androgens Log (Pansterone, k2, magnoil) Many people use supplements like DHEA, pregnenolone, and progesterone with the goal of raising their androgens and lowering estrogen. While this approach works for raising tissue levels of steroids...
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