androgenic

I have a bottle of source naturals 10mg pregnenolone in my kitchen cupboard. I want to try it for androgenic/ergogenic effects but I’m concerned it may cause problems as it seems pregnenolone is unpredictable on how people respond hormonally. If I take it and respond bad will discontinuing...

I think the sales of Coke/Pepsi are about to go through the roof. The study sounds like it was sponsored by one/both of the soda makers, but it was not, and in fact is corroborated by prior studies on (human) male fertility and sugar consumption that I posted about in the past. The study below...

Hi brothers, thought I’d given an update on my DHT gel journey for PE as I’ve finally hit the 20 week mark. I am proud of my modest gains that I have achieved and the confidence boost has been the best part especially the weekly comments I’ve been getting from my girl. AGE: 27 years old...

Welcome to Spellbreaker’s Ascending Muscle Solitarium (name under construction) In short, this will be a video log on my progress doing bodybuilding while incorporating Ray Peat’s views… mixed with my own. The current goal is to become healthier, more androgenic, feel better and gain muscle...

One of the core issues in modern endocrinology is the relatively weak correlation between serum levels of steroids and the overall activity in the organism associated with a particular steroid. For example, post-menopausal women have very low levels of estradiol yet very high whole-body...

Time to bring back Cistanche extract on the scene. This herb has a plethora of benefits and for anyone who is wondering, this herb is known as Rou Cong Rong in Chinese medicine. It is said to be a Yang tonic that benefits the kidneys, essence, and marrow (which includes the "sea of marrow"...

This product does not really need any introduction to anybody familiar with Peat's work. I have wanted to release it for a long time but over the last few months the studies I found related to the anabolic and anticatabolic effects of progesterone, combined with the fact that Peat has told quite...

I am posting this study as a response to the attacks I keep getting over email and PM, claiming that there absolutely no evidence for my statements that progesterone has androgenic effects (depending on the dose). As I mentioned in many other threads, progesterone is actually a true ligand for...

This post will be a bit long, but I hope it is worth it. I think @Jsaute21 and @dand will find it highly interesting but the information here applies just as much to females wishing to preserve lean tissue and prevent the catabolism that often occurs with aging. Here we go. Lately, I have been...

Ever since I read in one of Ray's articles about the ability of saturated fat to reverse even advanced liver fibrosis (cirrhosis) I have been researching the effects of various saturated fatty acids on a number of organs and tissues. A number of studies have been posted on the forum indicating...

Palmitic acid has a bad reputation in mainstream medicine and the blogosphere. It is claimed to directly cause insulin resistance, obesity and even hypogonadism. Well, these studies found the exact opposite. The first one found that methyl-palmitate (MP) is an actual androgen receptor agonist...

As I mentioned in a few past threads, androsterone was studied intensively in the first half of the 20th century and one of the reasons was its functional similarity to thyroid. In addition to its hypocholesterolemic effect androsterone was also found to be highly trophic to a number of organs...

Patients with prostate cancer are often treated with a combination of therapies such as 5-AR inhibitors to reduce production of DHT as well as other enzyme inhibitors to reduce conversion of DHEA into other downstream androgens. From the point of view of mainstream "treatment" for prostate...

Most people on the forum have read Peat's articles on PUFA and its great synergism with the estrogenic hormones. Peat has written that saturated fats have effects opposite to those of PUFA and there are studies showing feeding saturated fat increases androgen synthesis. I have been researching...

Edit (10/6/2022): Androsterone seems to be indeed a very effective precursor to DHT in-vivo, as demonstrated by the test results discussed in the thread below. https://raypeatforum.com/community/threads/idea-labs-hair-test-for-androgens.47974/post-856197 EDIT: Since I keep getting questions...

The steroids androsterone (A) and DHEA are considered not very strong androgens in terms of direct activity on androgenic receptors. DHEA is often cited as having 1/10 of the androgenic effects of testosterone (T) and androsterone as having 1/7 of the androgenic effects. While that has been...

I recently posted a study about DHT being required for male sexual behavior and orgasm. That study did not look specifically into whether DHT or one of its downstream metabolites was indeed responsible for male sexual function. This study went a bit further and claims that it is androsterone...

As promised, I am releasing a steroid that may be of interest to some people on the forum. It is a variation of the well-known steroid DHT that Peat has written about and I have also posted quite a few studies on. The steroid belongs to the group of the so-called keto-steroids and AFAIK this is...

I just posted a study showing that inhibition of SIRT1 is anti-estrogenic, and SIRT1 inhibitors like niacinamide have similar effects to the estrogen receptor antagonist fulvestrant. Niacinamide Is Anti-estrogenic | Ray Peat Forum This study shows that, again through inhibition of SIRT1...

I know that some forum members are considering taking or already are taking DHEA. As Peat has warned, and several studies confirmed, DHEA can be converted quite easily into estrogen if the dose used is too high or the person is under stress. In addition, there is some confusion about what route...