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androgen

  1. Cameron

    Want a beard? Take androsterone

    https://www.readcube.com/articles/10.1038/226869a0 Androsterone has the greatest effect as an androgen in beard growth 20 mgs a day sublingual
  2. Cameron

    T3 increases 5-AR type 1

    “In addition, in Silurana (Xenopus) tropicalis whole body larvae, T3 increases the expression of androgen-related genes, 5α-reductase type 1 (srd5alpha1) and ar (16). Therefore, the present study aimed to investigate whether TH- and sex steroid-related genes are also regulated by T3 in the brain...
  3. Brandin

    Injecting 11ketodht

    Hi could I inject the 11 ketodht in my rat and if so what is the best way?
  4. haidut

    Blocking androgens causes inflammation and prostate disease/cancer

    Yet another study striking directly the incredibly corrupt theory known as the "androgen hypothesis" - i.e. that androgens are the cause of many of the issues aging males experience, especially prostate enlargement (BPH) and/or prostate cancer. For almost a century now, the so-called standard of...
  5. haidut

    Age-related steroid deficiency may be treatable with niacinamide

    The study is actually about eye health, and the effects androgens play in it. However, the findings are not limited to the eyes and are in fact applicable for any other tissue/organ experiencing a decline in steroidogenesis with advancing age, which is basically all of them. As such, I am...
  6. haidut

    Prostate levels of androgens/DHT drastically lower in prostate cancer patients

    Yet another study, which raises serious doubts about the so-called "androgen hypothesis" of prostate cancer (PC). The study found that androgen levels, and especially DHT, are drastically (90%+) lower in PC than in people with benign prostate hyperplasia (BPH). In fact, 1/3 of the PC patients...
  7. Cameron

    Interesting study on testosterone gel topically for increasing terminal facial hair growth in young men. Topical androgens

    Topical androgens like androsterone and dht would likely have similar localized maturation effect of terminal hairs. Hacking beard growth. Male bio hacking. https://pubmed.ncbi.nlm.nih.gov/17852629/ —————————- Objectives: To determine whether the medical prescription of testosterone gel can...
  8. Cameron

    Androsterone and SHBG in training/supplementing androsterone would be of benefit in athletes

    “To determine how weight lifting training may affect serum and urinary androgens, we measured total serum testosterone (T), cortisol, sex hormone binding globulin (SHBG) and urinary testosterone, epitestosterone, androsterone, and etiocholanolone, in a group of 19 elite weight lifters after 20...
  9. haidut

    Fasting / stress decimate gonadal steroidogenesis, with no effect on blood cortisol

    A very interesting and very "controversial" (read: inconvenient truth) study, since it shows beyond reasonable doubt that even brief (4 days) fasting is a form of severe stress, at least when it comes to endocrine health. The study may also provide answers to various endocrine "mysteries"...
  10. haidut

    DHT may treat thyroid cancer

    Yet another "non-endocrine" tumor turns out to be anything but. Thyroid cancer rates have been rising for the last 30 years and parallel the increase in diagnoses of its likely precursor - i.e. the "autoimmune" disorder Hashimoto Disease. While there is solid evidence implicating endocrine...
  11. haidut

    DHT as anti-inflammatory as cortisol, but without the side effects

    As most of my readers know, glucocorticoids (synthetic or bioidentical) are widely used clinically and there is hardly a chronic conditions for which they are not prescribed even if only for managing brief "acute exacerbations". Despite mainstream medicine doing everything it can to conceal the...
  12. haidut

    DHT can stop aging of the pancreatic beta-cells (insulin-producing)

    Another great study, which demonstrates that far from being a "villain" (in both males and females) DHT is in fact a crucial and positive factor in health. In this specific study below, it was demonstrated that DHT dose-dependently inhibited the aging/dysfunction of the pancreatic beta-cells...
  13. haidut

    Scoliosis (even in females) may be driven by low androgen levels, DHT may treat it

    I am posting about this condition as it seems recently its numbers have absolutely exploded in the general population. Scoliosis used to be a relatively uncommon condition, usually present in adults over the age of 50. Mainstream medicine has no explanation for its possible causes, but suspects...
  14. Cameron

    Androgenic effects of T3 supplementation any experiences?

    “Thyroid hormones are important for growth and development of many tissues. Altered thyroid hormone status causes testicular abnormalities. For instance, juvenile hypothyroidism=neonatal transient hypothyroidism induces macroorchidism, increases testicular cell number (Sertoli, Leydig, and germ...
  15. haidut

    Stress ups cortisol/estrogen/prolactin, drops DHT, causes male infertility and prostate issues

    If you try to discuss infertility with a fertility/reproductive specialist or an endocrinologist, and mention that chronic stress may be a factor in infertility, you will probably get laughed out of the room. This is not just speculation. This exact same thing happened to several friends and...
  16. haidut

    DHT, not T, likely the "active" androgen in heart and brain

    Interesting study, done on baboons (so should have good relevance for humans), demonstrating that the cardiovascular system (CVS) exclusively accumulates and recognizes (at the receptor level) DHT, instead of testosterone (T). In fact, the androgen receptor in CVS is so structurally different it...
  17. haidut

    Estrogens cause obesity / PCOS in women, DHT is protective

    Female obesity and the closely related condition PCOS are perhaps the female equivalent of the so-called "androgen hypothesis" for balding and prostate cancer in men, as the female version of this hypothesis not only blames androgens for these conditions but specifically singles out DHT as the...
  18. haidut

    Low DHT can cause hypogonadism symptoms even in eugonadal men

    Seemingly contradictory title, but the study findings are pretty clear. Namely, even in males with normal testosterone levels there is a direct inverse relationship between DHT levels and symptoms of hypogonadism such as sexual dysfunction and "aging male" syndrome. For every 10% increase in DHT...
  19. haidut

    Androgens (T, DHT) highly protective against the flu

    A gem of a study that throws a wrench in one of medicine's core dogmas - i.e. androgens have detrimental effects on the immune system and males have evolved to live with a trade-off between high androgen levels (and as such high fertility) and higher risk of severe viral episodes that can be...
  20. cupofcoffee

    Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men

    https://link.springer.com/article/10.1007/s40618-021-01561-0
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