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androgen

  1. haidut

    Declining DHT in aging linked to cardiovascular disease (CVD)

    Yet another study demonstrating that the "villain of all males around the world" - the dastardly androgen dihydrotestosterone (DHT) - actually is, in all likelihood, beneficial for males, at least when it comes to their cardiovascular health. However, since CVD is one of the risk factors for...
    • haidut
    • Thread
    • androgen calcification cvd dht dihydrotestosterone inflammation stiffness vascular
    • Replies: 2
    • Forum: Scientific Studies
  2. Cameron

    All about increasing 5 alpha reductase in the face and tissues for beard growth and masculine facial structure

    Let’s get a discussion on best ways to truly up regulate androgens and 5-ar (in the skin and tissue) primarily the expression in the face. Beard maxing looks maxing and masculine jaw maxing Results: Testosterone was taken up by both cell types; significant amounts of 5...
    • Cameron
    • Thread
    • androgen beard testosterone males
    • Replies: 33
    • Forum: Male Issues
  3. haidut

    Fasting decreases androgens, increases aldosterone (and possibly cortisol/estrogens) in women

    I often get criticized that I rely too much on animal studies, so here is a human one that should give the proponents of caloric restriction / fasting a pause. Even a short fast (24-48 hours) resulted in decreased androgen synthesis in women, while increasing aldosterone. In general, fasting...
    • haidut
    • Thread
    • aldosterone androgen caloric restriction cortisol estrogen fasting steroid
    • Replies: 1
    • Forum: Scientific Studies
  4. miquelangeles

    Androgen Biosynthesis in the Stomach

    For the last ~6 months I've been experimenting with pregnenolone in different dosages, frequencies, schedule and routes of administration. There are already numerous threads about it's effects (they are very different depending on all those factors), but I want to mention two things that I...
  5. haidut

    Low testosterone detrimental, TRT beneficial for men with COVID-19

    Within a month of the pandemic start back in early 2020, doctors were already noticing a gender-specific trend in COVID-19 cases. Namely, pre-menopausal women fared much better in terms of COVID-19 disease course compared to post-menopausal women and (adult) men. The ever-corrupt Big Pharma was...
    • haidut
    • Thread
    • androgen covid-19 hospitalization ichh immunity testosterone trt
    • Replies: 9
    • Forum: Scientific Studies
  6. Cameron

    Want a beard? Take androsterone

    https://www.readcube.com/articles/10.1038/226869a0 Androsterone has the greatest effect as an androgen in beard growth 20 mgs a day sublingual
    • Cameron
    • Thread
    • androgen androsterone beard hair
    • Replies: 19
    • Forum: Male Issues
  7. Cameron

    T3 increases 5-AR type 1

    “In addition, in Silurana (Xenopus) tropicalis whole body larvae, T3 increases the expression of androgen-related genes, 5α-reductase type 1 (srd5alpha1) and ar (16). Therefore, the present study aimed to investigate whether TH- and sex steroid-related genes are also regulated by T3 in the brain...
  8. Brandin

    Injecting 11ketodht

    Hi could I inject the 11 ketodht in my rat and if so what is the best way?
  9. haidut

    Blocking androgens causes inflammation and prostate disease/cancer

    Yet another study striking directly the incredibly corrupt theory known as the "androgen hypothesis" - i.e. that androgens are the cause of many of the issues aging males experience, especially prostate enlargement (BPH) and/or prostate cancer. For almost a century now, the so-called standard of...
    • haidut
    • Thread
    • androgen bph cancer dht dihydrotestosterone inflammation prostate prostate cancer
    • Replies: 2
    • Forum: Scientific Studies
  10. haidut

    Age-related steroid deficiency may be treatable with niacinamide

    The study is actually about eye health, and the effects androgens play in it. However, the findings are not limited to the eyes and are in fact applicable for any other tissue/organ experiencing a decline in steroidogenesis with advancing age, which is basically all of them. As such, I am...
    • haidut
    • Thread
    • aging androgen dry eye eye hypogonadism meibomian nad niacinamide nicotinamide nicotinamide mononucleotide nicotinamide riboside nmn nr steroidogenesis
    • Replies: 12
    • Forum: Scientific Studies
  11. haidut

    Prostate levels of androgens/DHT drastically lower in prostate cancer patients

    Yet another study, which raises serious doubts about the so-called "androgen hypothesis" of prostate cancer (PC). The study found that androgen levels, and especially DHT, are drastically (90%+) lower in PC than in people with benign prostate hyperplasia (BPH). In fact, 1/3 of the PC patients...
    • haidut
    • Thread
    • androgen bph cancer dht dihydrotestosterone prostate cancer testosterone
    • Replies: 1
    • Forum: Scientific Studies
  12. Cameron

    Interesting study on testosterone gel topically for increasing terminal facial hair growth in young men. Topical androgens

    Topical androgens like androsterone and dht would likely have similar localized maturation effect of terminal hairs. Hacking beard growth. Male bio hacking. https://pubmed.ncbi.nlm.nih.gov/17852629/ —————————- Objectives: To determine whether the medical prescription of testosterone gel can...
    • Cameron
    • Thread
    • androgen beard men testosterone
    • Replies: 25
    • Forum: Male Issues
  13. Cameron

    Androsterone and SHBG in training/supplementing androsterone would be of benefit in athletes

    “To determine how weight lifting training may affect serum and urinary androgens, we measured total serum testosterone (T), cortisol, sex hormone binding globulin (SHBG) and urinary testosterone, epitestosterone, androsterone, and etiocholanolone, in a group of 19 elite weight lifters after 20...
    • Cameron
    • Thread
    • androgen androsterone shbg testosterone
    • Replies: 0
    • Forum: Male Issues
  14. haidut

    Fasting / stress decimate gonadal steroidogenesis, with no effect on blood cortisol

    A very interesting and very "controversial" (read: inconvenient truth) study, since it shows beyond reasonable doubt that even brief (4 days) fasting is a form of severe stress, at least when it comes to endocrine health. The study may also provide answers to various endocrine "mysteries"...
    • haidut
    • Thread
    • androgen atrophy cortisol fasting gonads hypogonadism stress
    • Replies: 14
    • Forum: Scientific Studies
  15. haidut

    DHT may treat thyroid cancer

    Yet another "non-endocrine" tumor turns out to be anything but. Thyroid cancer rates have been rising for the last 30 years and parallel the increase in diagnoses of its likely precursor - i.e. the "autoimmune" disorder Hashimoto Disease. While there is solid evidence implicating endocrine...
    • haidut
    • Thread
    • androgen cancer dht disruptor endocrine hashimoto thyroid
    • Replies: 1
    • Forum: Scientific Studies
  16. haidut

    DHT as anti-inflammatory as cortisol, but without the side effects

    As most of my readers know, glucocorticoids (synthetic or bioidentical) are widely used clinically and there is hardly a chronic conditions for which they are not prescribed even if only for managing brief "acute exacerbations". Despite mainstream medicine doing everything it can to conceal the...
    • haidut
    • Thread
    • androgen chronic cortisol dht gastritis glucocorticoid inflammation
    • Replies: 5
    • Forum: Scientific Studies
  17. haidut

    DHT can stop aging of the pancreatic beta-cells (insulin-producing)

    Another great study, which demonstrates that far from being a "villain" (in both males and females) DHT is in fact a crucial and positive factor in health. In this specific study below, it was demonstrated that DHT dose-dependently inhibited the aging/dysfunction of the pancreatic beta-cells...
    • haidut
    • Thread
    • aging androgen beta-cells dht diabetes insulin pancreas senescence
    • Replies: 0
    • Forum: Scientific Studies
  18. haidut

    Scoliosis (even in females) may be driven by low androgen levels, DHT may treat it

    I am posting about this condition as it seems recently its numbers have absolutely exploded in the general population. Scoliosis used to be a relatively uncommon condition, usually present in adults over the age of 50. Mainstream medicine has no explanation for its possible causes, but suspects...
  19. Cameron

    Androgenic effects of T3 supplementation any experiences?

    “Thyroid hormones are important for growth and development of many tissues. Altered thyroid hormone status causes testicular abnormalities. For instance, juvenile hypothyroidism=neonatal transient hypothyroidism induces macroorchidism, increases testicular cell number (Sertoli, Leydig, and germ...
    • Cameron
    • Thread
    • anabolic androgen metaboic t3 t3 + t4 t3 thyroid
    • Replies: 7
    • Forum: Metabolism
  20. haidut

    Stress ups cortisol/estrogen/prolactin, drops DHT, causes male infertility and prostate issues

    If you try to discuss infertility with a fertility/reproductive specialist or an endocrinologist, and mention that chronic stress may be a factor in infertility, you will probably get laughed out of the room. This is not just speculation. This exact same thing happened to several friends and...
    • haidut
    • Thread
    • androgen aromatase cortisol dht estrogen fertility hypogonadism infertility prolactin stress
    • Replies: 0
    • Forum: Scientific Studies
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