I am posting this study as a response to the attacks I keep getting over email and PM, claiming that there absolutely no evidence for my statements that progesterone has androgenic effects (depending on the dose). As I mentioned in many other threads, progesterone is actually a true ligand for...
Palmitic acid has a bad reputation in mainstream medicine and the blogosphere. It is claimed to directly cause insulin resistance, obesity and even hypogonadism. Well, these studies found the exact opposite. The first one found that methyl-palmitate (MP) is an actual androgen receptor agonist...
As many of you know by now, I have acquired an interest lately to research the connection between the process of saturation of various nutrients and steroids and the effects of this saturation on the properties of these substances. After doing some work on androgens such as androsterone and...
If you take a look at a standard diagram of steroigenesis and metabolism you will see that the androgen DHT can be synthesized via only one route, namely DHEA->Androstenedione->Testosterone->DHT. Recently, some studies have shown that DHT can also be synthesized via an alternative pathway, still...
Patients with prostate cancer are often treated with a combination of therapies such as 5-AR inhibitors to reduce production of DHT as well as other enzyme inhibitors to reduce conversion of DHEA into other downstream androgens. From the point of view of mainstream "treatment" for prostate...