alzheimer's

  1. P

    Brain Insulin Resistance Identified As Possible New Link Between Alzheimer's Disease, Diabetes

    It says brains inability to burn glucose is responsible for Alzheimer's disease.caused by insulin's resistance in brain, and that probably mediated by inflammation. Brain Insulin Resistance Contributes to Cognitive Decline in Alzheimer's Disease – PR News...
  2. haidut

    Blocking PUFA Metabolism May Reverse Alzheimer Disease (AD)

    I posted a few studied showing PUFA and its metabolites are strongly involved in AD and brain aging in general. Increased Pufa Oxidation May Be Biomarker For Alzheimers Blocking Inflammation From PUFA Reverses Brain Aging The second link above discussed specifically the inhibition of the...
    • haidut
    • Thread
    • alox15 alzheimer's brain inflammation inhibitor leukotrienes lipoxygenase lox
    • Replies: 11
    • Forum: Scientific Studies
  3. haidut

    Endotoxin (LPS) May Be A Causative Factor In Alzheimer Disease (AD)

    I posted recently about a study that found many of the chronic degenerative diseases can be traced back to endotoxin and excess iron. Endotoxin And Iron Finally Recognized As Potential Causes Of Many Diseases This study went a step further and identified endotoxin (LPS) in the brains of AD...
    • haidut
    • Thread
    • alzheimer's bacteria brain endotoxin lps neurodegenerative tlr4
    • Replies: 17
    • Forum: Scientific Studies
  4. haidut

    5α-Dihydroprogesterone (5α-DHP) - Potent Role In Neurodegenerative Conditions

    While researching saturated steroids and their effects on the brain, I noticed a number of highly promosing studies demonstrating benefit of such steroid for a variety of neurodegenerative conditions such as MS, ALS, Alzheimer, Parkinson, etc. Ray has written extensively on the topic of...
    • haidut
    • Thread
    • 5α-dhp 5α-dihydroprogesterone als alzheimer's antiaging brain diabetes multiple sclerosis neurodegenerative neuropathy neurosteroid tbi
    • Replies: 13
    • Forum: Scientific Studies
  5. haidut

    5α-Dihydroprogesterone (5α-DHP) - The Primary Progestogen Neurosteroid

    It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
    • haidut
    • Thread
    • 5α-dhp 5α-dihydroprogesterone alzheimer's antidepressant antiestrogen brain cns dementia gaba glycine ms neurosteroid parkinson's protective
    • Replies: 25
    • Forum: Scientific Studies
  6. ecstatichamster

    Supposed Alzheimers Plaques Show Up In Clear Thinking Aged People

    Don't have a study as this was just presented: https://www.sciencedaily.com/releases/2016/11/161116132813.htm Not surprisingly, the entire Alzheimer's treatment community will still be doing the same things, even though these amyloid-beta plaques probably have nothing to do with the problem.
  7. L

    Radiation May Contribute To Development Of Alzheimer's

    Concern that radiation may contribute to development of Alzheimer's https://www.sciencedaily.com/releases/2016/10/161027122751.htm
    • lollipop
    • Thread
    • alzheimer's article health radiation
    • Replies: 0
    • Forum: Alzheimer's
  8. haidut

    Vitamin D3 Extends Lifespan By Preventing Toxic Protein Buildup

    Over the last 6-9 months I noticed that often people who communicate with Peat over email get a recommendation to supplement with vitamin D. When asked why, Peat said that he knows quite a few people who recovered from "very serious symptoms" by using vitamin D. Well, this new study shows that...
    • haidut
    • Thread
    • aging alzheimer's brain cholecalciferol condition extension homeostasis lifespan neurodegenerative parkinson's protein study vitamin d
    • Replies: 21
    • Forum: Scientific Studies
  9. haidut

    Testosterone Deprivation For Prostate Cancer Causes Dementia / Alzheimer

    Not surprising at all, and very common these days. Take one drug or treatment approach and not only you don't get any actual cure but you also get another nasty condition as a side effect. The barbaric treatment of prostate cancer (castration) is now officially known to lead to dementia in the...
    • haidut
    • Thread
    • adt alzheimer's androgen deprivation castration dementia prostate cancer
    • Replies: 3
    • Forum: Cancer
  10. M

    Endotoxin And Iron Finally Recognized As Potential Causes Of Many Diseases

    [ moderator edit: threads merged ] Bacteria lurking in blood could be culprit in countless diseases
    • Miso
    • Thread
    • als alzheimer's arthritis bse cancer clotting cvd endotoxin fibrin heart attack inflammation iron lps stroke thrombosis
    • Replies: 55
    • Forum: Scientific Studies
  11. haidut

    RoundUp (glyphosate) Linked To Alzheimers, Parkinson And ALS

    I posted about a similar study a few months ago, but this time the scientists are directly making the claim that RoundUp is causally involved with these conditions. The mechanism of action is again glycine antagonism / deletion by glyphosate. Monsanto's Roundup Weedkiller Linked to Alzheimer's...
    • haidut
    • Thread
    • als alzheimer's glycine glyphosate parkinson's roundup
    • Replies: 4
    • Forum: Scientific Studies
  12. haidut

    Stress Increases Risk For Alzheimer Disease (AD)

    This is probably not surprising for any forum user, but official medical guidelines still claim that stress has no known long-term direct effects on health except in "genetically-predisposed individuals". Stress may increase risk for Alzheimer’s disease "...Fewer than ten percent of Alzheimer...
  13. haidut

    Serotonin Antagonists As Therapy For Alzheimer Disease

    As I posted in another thread, over 90% of the drugs tested for Alzheimer during the last 10 years have veen utter and abject failure. This is a pretty solid indication that the theory of Alzheimer's pathology and proposed beneficial pathways on which these drugs were based is solidly wrong...
    • haidut
    • Thread
    • 5-ht6 alzheimer's antagonist disease idalopirdine receptor serotonin therapeutic
    • Replies: 14
    • Forum: Scientific Studies
  14. Drareg

    Alzheimers And T3,Rt3

    Ray Peat has written and spoken about Alzheimers and dementia in general. These studies are small but very interesting, I don't understand why they don't check T3 and reverse T3 for Alzheimers.This is all I can find at the moment. Study showing T3 is low in Alzheimers patients . Low Levels...
  15. haidut

    Dementia Breakthrough - Alzheimer Disease Linked To Endotoxin And Iron

    Nice to see medicine may be finally making a 180-degree turn but I would not hold my breath for it to become mainstream treatment any time soon. Given the abilities of aspirin to chelate iron directly from the brain, this may be one of the reasons for its beneficial effects on Alzheimer's...
  16. P

    Metabolism Of Galactose In The Brain And Liver Of Rats And Its Conversion Into Glutamate And Other A

    Metabolism of galactose in the brain and liver of rats and its conversion into glutamate and other amino acids. - PubMed - NCBI Abstract Time- and dose-dependent measurements of metabolites of galactose (with glucose as control) in various organs of rats are discussed. Not only the liver but...
    • paymanz
    • Thread
    • alzheimer's ammonia brain gaba galactose glutamate glutamine lactose study
    • Replies: 1
    • Forum: Scientific Studies
  17. haidut

    Anti-acid Drugs (ppi) May Cause Dementia

    The so-called Proton Pump Inhibitors (PPI) are second generation anti-acid drugs that replaced the much safer first generation H2 antagonists like fomotidine, ranitidine, cimetidine, etc. The PPIs are really bad drugs that should have never been approved considering that they provably cause...
  18. ken

    A Seven Year Late Look At Results Of Phase 2 Trial Of Rember

    Whither Methylene Blue (TRx0237) in Alzheimer's? - Pathophilia This site has another interesting article on using closed distributions to keep generic manufacturers from competing with orphan drugs.
    • ken
    • Thread
    • alzheimer's article methylene blue
    • Replies: 0
    • Forum: Articles
  19. haidut

    Estrogen (estradiol) Promotes Autoimmunity

    If there is any doubt in anybody's mind about the role of estrogen as a cause of autoimmune conditions I hope that his will clarify the situation some more. The excerpt below is from the study on adrenals and Alzheimers I posted today but I thought that this excerpt deserves its own thread given...
    • haidut
    • Thread
    • aging alzheimer's autoimmune autoimmunity estradiol estrogen immunodeficiency
    • Replies: 6
    • Forum: Scientific Studies
  20. haidut

    Alzheimer Patients Have "aged" Adrenals, Higher Cortisol And Estrone

    Ray has written several times about the changes that occur in the adrenals with aging and stress/hypothyroidism. The adrenal layers change in structure and activity in a way that favors zona glomerulosa, which results in higher production of cortisol and estrogen. This study seems to confirm...
    • haidut
    • Thread
    • adrenals aging alzheimer's blood-brain barrier cortisol estrone study
    • Replies: 4
    • Forum: Scientific Studies
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