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alzheimer's

  1. 'peataphysique

    Childhood dementia claiming young lives | A Current Affair

  2. Mauritio

    Serotonin, PUFA and histamine increase leaky brain

    This is just just another angle showing how stress hormones and PUFA affect the whole body negatively. Increased Blood-brain-barrier permeability(leaky brain) is linked to many diseases : "Blood–brain barrier dysfunction contributes to pathology in a range of neurological conditions including...
  3. cupofcoffee

    Coffee polyphenols ameliorate cognitive decline via maintenance of blood-brain barrier (BBB) integrity in senescence-accelerated mouse prone 8 (SAMP8)

    https://www.jstage.jst.go.jp/article/jpssuppl/94/0/94_1-O-C3-4/_article/-char/en
  4. Mauritio

    Cistanche increases steroidogenic enzymes, lowers NO, helps osteoporosis and Alzheimer's

    I posted these studies in another thread, but I feel they deserve their own thread as they show that cistanche is helping the body on a systemic level. A few new studies on cistanche tubulosa: This one shows that cistanche increases biosynthesis of testosterone by increasing important...
  5. Tristan Loscha

    Calcitriol+VDR:Increased Activity Of P-Glycoprotein=Decrease Of HAβ42 Plaque

    J Neurochem. Author manuscript; available in PMC 2013 Dec 1. Published in final edited form as: J Neurochem. 2012 Dec; 123(6): 944–953. Published online 2012 Nov 1. doi: 10.1111/jnc.12041 PMCID: PMC3538370 NIHMSID: NIHMS413573 PMID: 23035695 1α,25-Dihydroxyvitamin D3-Liganded Vitamin D Receptor...
  6. haidut

    Low Dose Lithium May Stop Alzheimer’s Disease (AD) In Its Tracks

    This study was sent to me by one of my Twitter followers. In some of my past interviews/podcasts, I did mention isolated published case studies, as well as anecdotal medical reports of even advanced cases of AD getting rapidly reversed by micro-dosing regimens using lithium salts such as...
  7. haidut

    Metabolic Dysfunction Is A Primary Cause Of Aging And Its Symptom Alzheimer Disease (AD)

    As it seems, not all hope is lost when it comes to mainstream medicine. Just a few days ago I posted about a landmark human study with AD demonstrating that the a low daily dose of the cheap, unpatentable chemical methylene blue (MB) may stop AD. LSD may do the same, and both MB and LSD likely...
  8. haidut

    LSD Enters Clinical Trials For Alzheimer Disease (AD)

    For the last 5+ decades, Big Pharma and public health officials together with the entire law enforcement apparatus have been propagating myths, lies and outright fraud in regards to psychedelic drugs and especially about LSD. This attitude grew out of the civil rights movement and protests in...
  9. haidut

    Increasing Metabolism May Reverse Alzheimer Disease (AD) And General Aging

    Yet another study demonstrating the remarkable parallels between the decline in function (metabolism) and the structural abnormalities that occur not only in specific pathologies such as AD but also in the generalized degradation known as "aging". FDA currently does not recognize aging as a...
  10. haidut

    Low-dose Methylene Blue (MB) May Stop Alzheimer Disease (AD)

    Another great result for the humble dye whose only claim medical fame so far has been as treatment for malaria, and even that "designation" has largely been deprecated due to the advent of new and "improved" drugs. About a decade ago, a company in the UK started researching MB as potential...
  11. haidut

    Allopregnanolone As A Treatment Of Alzheimer Disease (AD)

    It looks like the recent FDA approval of allopregnanolone (ALLO) for postpartum depression may open the floodgates to ton of new research with this steroid, as well as with its reliable precursors such as pregnenolone and progesterone. I posted several studies in the past demonstrating that...
  12. haidut

    Pregnenolone Is A Potent (functional) Endotoxin (TLR4) Antagonist

    It seems that pregnenolone is finally starting to look exciting to the medical industry. In addition for its intensive studies for a variety of mental issues, now studies are coming out demonstrating its endotoxin (LPS) antagonism effects. As most forum users know, endotoxin exerts its effects...
  13. haidut

    Increased Cholesterol Esterification As A Cause Of Alzheimer Disease (AD)

    Peat's most recent newsletter was on the topic of cholesterol and its increased esterification as a possible cause of the many pathologies that occur with aging. Nov 2018: Dr. Peat Talks About Cholesterol Esters Causing Aging One of the organs most vulnerable to cholesterol esterification is...
  14. haidut

    Stress And Learned Helplessness May Be The Main Cause Of Dementia

    A great study showing that controlling for factors such as sex, marital status, lower educational level, lifestyle factors, existing chronic and acute disease, substance abuse, etc did NOT change dementia risk. The only thing that correlated (likely causatively) with risk of dementia (e.g...
  15. haidut

    Periodontal Disease Can Cause Alzheimer's Disease (AD)

    Peat has written many times on the link between periodontal disease, and endotoxin. He mentioned how a few dentists he knows stopped doing dental cleaning after they found that that giving their patients laxatives or antibiotics cured their gum disease. In addition, a few studies came out...
  16. haidut

    Bile Acid Stimulates Mitochondrial Function, Could Treat Parkinson And Alzheimer's

    I posted a few studied some time ago showing that bile acids increase metabolism but stimulating the synthesis of T3. This increase in metabolism is perhaps the main mechanism behind the ability of "obesity surgery" to provide long-term benefits for the people who undergo the procedure. Aside...
  17. haidut

    Canola Oil (PUFA) Causes Obesity, Memory Impairment, And Likely Alzheimer Disease (AD)

    I really like this study because it is one of the few that examine the direct effects of adding PUFA to the diet. As such, it serves to expose the fraudulent "science" that led to the replacement of healthier oils (like beef tallow, butter, olive oil) in the Western diet with the cheap...
  18. haidut

    Another Human Study Shows Methylene Blue (MB) May Treat Alzheimer Disease (AD) If Used On Its Own

    A few months ago, a thread was posted about the news published by mainstream media that MB "failed" in a human trial for AD. It only failed when it was combined with other drugs currently used for AD, as those drugs are mostly cholinergic and highly excitotxic. When used on its own, MB showed...
  19. haidut

    Niacinamide And Doxycycline May Treat Alzheimer Disease (AD)

    This study is yet another one that shows benefit of raising NAD levels for treating neurodegenerative conditions like AD. There were a few older studies around 2003, which were also done on mice and as a result of those studies a human clinical trial with 3g niacinamide daily (a dose that...
  20. haidut

    Human Study Confirms Alzheimer As A Metabolic Condition (brain Diabetes)

    Over the last 3 years I posted quite a few studies on Alzheimer disease (AD) and have discussed it at length in the Danny Roddy podcasts. Among the most successful interventions are niacinamide and methylene blue (MB) both of which are in human clinical trials, thyroid and aspirin. Alzheimer...
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