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allopregnanolone
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Low-dose Allopregnanolone Induces Relief From Depression In Just 24 Hours
I posted a few studies on the powerful mood boosting effects of allopregnanolone in relation to its precursor 5a-DHP. The precursor 5a-DHP converts into allopregnanolone with almost 100% efficiency as it is the the only pathway through which it can be metabolized downstream. All successful...- haidut
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- allopregnanolone brexanolone depression low dose postpartum rapid relief sustained
- Replies: 41
- Forum: Scientific Studies
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Finasteride Causes Physical Damage To Nerves, Depression, ED, Steroid Imbalance
After a decade of denying that a thing such as PFS exists, mainstream medicine seems to be wisening up to the fact that this poison does a lot more than lower the "bad" DHT. Up until very recently, it was common to simply measure blood steroid levels and then declare that they had rebounded upon...- haidut
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- 5a-dhp allopregnanolone damage depression dhea dht edd erectile dysfunction finasteride imbalance mdd nerve nervous system pregnenolone progesterone pudental steroid
- Replies: 41
- Forum: Scientific Studies
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Allopreg {write Up}
Hey guys- did a short write up for allopreg with a lot of the work from here plus some other in depth studies I came across. -
Effects Of Morphine Dependence And Withdrawal On Levels Of Neurosteroids In Rat Brain
Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain. - PubMed - NCBI It's a rat study but I think the results are applicable to humans. "The chronic morphine administration (ip) resulted in a marked decrease in the brain concentrations of pregnenolone (PREG)...- BigYellowLemon
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- allopregnanolone dhea dhea-s morphine naloxone naltrexone neurosteroid opioids pregnenolone progesterone steroids
- Replies: 5
- Forum: Scientific Studies
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Pregnenolone As A Treatment For Loneliness
I touched upon this idea/topic in some of my other posts, and just like those other posts, I would like to emphasize here that I am not suggesting steroid supplementation as a substitute for social interaction. The purpose of this post if to provide some insight on the biochemical effects of...- haidut
- Thread
- 5a-dhp 5α-dhp 5α-dihydroprogesterone allopregnanolone depression hpa loneliness mental health pregnenolone progesterone
- Replies: 52
- Forum: Scientific Studies
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5α-DHP - Liquid 5α-Dihydroprogesterone For Lab/R&D
****DISCONTINUED****DISCONTINUED****DISCONTINUED**** Replaced by allopregnanolone, which is a direct metabolite of 5α-Dihydroprogesterone (5α-DHP). https://raypeatforum.com/community/threads/allop-liquid-allopregnanolone-for-lab-r-d.41055/... -
The Role Of Steroids In The Prediction Of Affective Disorders In Adult Men
https://www.ncbi.nlm.nih.gov/pubmed/27871861?dopt=Abstract- Koveras
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- allopregnanolone androsterone anxiety depression pregnenolone progesterone steroids testosterone
- Replies: 13
- Forum: Scientific Studies
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Pregnenolone Is The Most Potent Inhibitor Of The Stress Signal (CRH)
I think this study should finally put to rest the arguments and debates of whether pregnenolone raises or lowers cortisol, and how it affects the stress response overall. I posted a similar study, which showed that the pregnenolone metabolites progesterone and allopregannolone potently inhibited...- haidut
- Thread
- acth allopregnanolone artemisia cortisol crf crh inhibitor pregnenolone stress
- Replies: 116
- Forum: Scientific Studies
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Progesterone, Testosterone, Allopregnanolone Are Serotonin Antagonists
This study shows that some of the gonadal steroids act in a manner similar to the drug ondansetron - i.e. antagonize the 5-HT3 "receptor". While pregnenolone sulfate was not antagonistic to 5-HT3, taking pregnenolone metabolizes mostly into progesterone and allopregnanolone. So, it seems like a...- haidut
- Thread
- 5ht allopregnanolone antagonist progesterone serotonin study testosterone
- Replies: 24
- Forum: Scientific Studies