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alcohol

  1. youngsinatra

    Best Supplements For Enhancing Alcohol Tolerance?

    I have a big meet-up with a dozen of old friends this weekend and we plan on partying hard. I wonder what could help with alcohol tolerance? I‘ve heard @haidut saying that aromatase inhibition can help with alcohol clearance? I personally plan on taking high dose thiamin HCL (1-2 grams) +...
  2. haidut

    Vitamin B1 can reverse heart damage/failure caused by alcoholism

    The beneficial effects of vitamin B1 (thiamine) on the nervous system have been known for a long time, and the vitamin is routinely used in hospitals around the world to treat both acute alcohol intoxication as well as the nervous system damage known as Wernicke-Korsakoff syndrome caused by...
  3. J

    The health effects of 1 - 2 drinks daily

    I was reading posts in the hair section how alcohol can help with breaking down calcification which is why homeless can have a ton of hair despite having horrible nutrition. Can having 1-2 drinks daily be healthy or beneficial? I like tequila with juice and apple ciders. I'm not drinking any...
  4. Hans

    Alcohol increases neurogenesis

    This was an interesting study that I thought was worth sharing. Many detrimental substances/compounds/neurotransmitters/hormones, are able to increase neurogenesis and are supposed to be beneficial. This study made me think of what Peat said about certain SSRI drugs increasing allopregnanolone...
  5. Lokzo

    Who Feels Euphoric The Day After Alcohol? (Alcohol Afterglow)

  6. haidut

    Alcohol Causes Liver (and Other Organ) Damage By Lowering NAD/NADH Ratio

    A neat little study, which demonstrates once again the crucial role of energy and optimal redox status in a public health issue that has now reached catastrophic proportions. Namely, alcohol-related morbidity and mortality. Those have always been an issue in any developed country but since the...
  7. haidut

    Alcohol Brain Damage Due To Iron Accumulation; Vitamin B1 To The Rescue

    Chronic alcohol abuse is highly detrimental to health and especially to the brain. Alcohol puts the body in a reductive state and depletes vitamin B1 (thiamine) stores. If the B1 deficiency becomes severe enough it manifests through what is clinically known as Wernicke-Korsakoff syndrome (WKS)...
  8. haidut

    Blocking Serotonin, Adrenaline Treats Anxiety, Brain Damage Due To Alcohol "addiction"

    Over the last 2 decades a large number of studies have come out demonstrating that the withdrawal symptoms in "addicts" are due largely due to elevated serotonin and adrenaline. As such, drugs such as cyproheptadine, clonidine, propranolol, etc have been successfully used off-label for treating...
  9. haidut

    Supplementation With (long Chain) Saturated Fats Protects Liver From Alcohol

    As many of my readers already know, there are a number of human studies, going back to at least the 1960s, demonstrating that supplementation with saturated fats (SFA) protects the liver from damage induced by alcohol. I fact, supplementation with SFA not only prevents alcohol-induced liver...
  10. haidut

    Niacinamide Can Treat Alcoholic Liver Disease

    As many forum users have probably heard on the news, alcohol abuse is now a leading cause of death in young people under 35. It is projected to soon surpass drug overdose as a cause of death in this demographic. Millennials are dying of alcohol-related liver disease at increasing rates The...
  11. haidut

    PUFA Increases Alcohol Damage By Increasing Cell Fluidity; SFA Are Protective

    Peat has written a number of times on the synergies of PUFA with ethanol and endotoxin on causing liver and systemic damage. In one of his articles he opined that in the absense of PUFA/iron ethanol would likely not cause much harm. He also wrote about the protective effects of saturated fats...
  12. haidut

    Alcohol Mostly Benign For The Liver, Causing Injury Requires Endotoxin (LPS)

    Peat wrote in one of his articles that alcohol is getting a bad reputation for causing all sorts of liver disease and even liver cancer, but alcohol by itself is fairly neutral for the liver and that the role of PUFA, iron and endotoxin is being neglected by mainstream medicine. The study below...
  13. haidut

    Alcohol "addiction" Driven By Endotoxin (TLR4)

    I posted a few threads in the past about addiction, and especially alcohol addiction being driven by high cortisol and low dopamine. This new study adds more pieces to the puzzle by implicating endotoxin in that process as well. Just as importantly, the study found that the desire to drink...
  14. haidut

    Thyroid May Treat Fetal Alcohol Syndrome (FAS)

    The so-called fetal alcohol syndrome has been on the rise over the last 2 decades and its symptoms largely overlap with the "adult" alcohol syndrome or at least the behavioral parts of it. Broda Barnes once wrote that he never treated an alcoholic who was not also hypothyroid and that he also...
  15. haidut

    Candida Overgrowth Is A Major Factor In (alcoholic) Liver Damage / Cirrhosis

    Over the last 5 years or so it has become very fashionable among many "naturopaths" to throw the diagnosis "Candida overgrowth" at every symptom of gut dysfunction people present with at the doctor. Peat has spoken about Candida overgrowth and how the fungus typically only becomes an issue in...
  16. haidut

    Loneliness Increases Alcohol Tolerance, May Explain "addiction"

    I posted several studies in the past about the connection between stress hormones and "addiction", especially alcohol. This new study adds more evidence to that link and now also draws serotonin in the picture. Apparently, social creatures are much more sensitive to inebriation effects of...
  17. haidut

    Stress Leads To Lower Dopamine And More Drinking

    The study was really on alcohol consumption what affects it. It has been known since the 1960s that people drink more when under stress but to this day mainstream medicine denies that there is a causative link between stress and substance abuse. I posted a few studies showing that "addicts" have...
  18. haidut

    Low-dose Glycine May Treat Alcoholic Delirium / Hallucinosis In Humans

    The symptoms of alcohol withdrawal and its associated delirium are due mostly to serotonin overload and functional GABA deficiency. As such, anti-serotonin drugs can be very beneficial but they often have side effects and cannot be freely obtained. This human study showed that a single...
  19. haidut

    Dopaminergic Drugs Like Bromocriptine May Treat Alcoholilsm

    This study is interesting for several reasons. On one hand, it combines well with previous studies on addiction I posted about - i.e. that "addiction" is a physiological state in which a person attempts to mitigate the effects of "inescapable stress" as animal studies commonly call the issue...
  20. E

    Testosterone Increases In Men After A Low Dose Of Alcohol

    Testosterone increases in men after a low dose of alcohol. - PubMed - NCBI After intake of alcohol (0.5 g/kg, 10% w/v), an acute increase in plasma testosterone (from 13.5 +/- 1.2 nmol/liter to 16.0 +/- 1.6 nmol/liter, mean +/- SEM; p < 0.05), a decrease in androstenedione (from 5.1 +/- 0.4...
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