1. teds

    Alcohol and flushing

    I don’t drink often! But when I have an event and want a glass of wine the red face and the heat is soooooo intense… possibly worse since I have been drinking less (last 15 years).. has anyone worked out how to reduce the vasodilatory effects of alcohol?
  2. haidut

    Big Pharma - oral GABA doesn't work; Also Big Pharma - oral GABA works, can replace alcohol

    We are now living in an openly clown world, so I don't really expect many doctors to change their position based on contrarian evidence, but it is a stunning admission on behalf of medicine regardless. Namely, mainstream medicine and its partners in crime (often, literally) Big Pharma have spend...
  3. Mauritio

    Pregnenolone reduces alcohol cravings in humans

    This study showed that giving people 300 or 500mg of Pregnenolone reduced cravings in alcoholics and also normalized their stress parameters like cortisol and ACTH. I cant get the full text, but the abstract only mentions the 300mg dose as effective, so I'm not sure about the 500mg dose. But...
  4. Mauritio

    Alcohol only causes fatty liver when consumed with PUFA not with SFAs

    In this study they authors studied how the intake of saturated and unsaturated fats affect the effect of alchohol on the body. They looked at he usual things that alcohol consumption causes in the body (necrosis, fatty liver and inflammation), while also feeding the animals fish oil, corn oil...
  5. Ras

    Anti-Aging Breakthrough: Detoxing Body of Harmful Fat By-Products To Extend Lifespan

    The study discussed here presents evidence that clearing the body of the fat byproducts glycerol and glyceraldehyde could lead to an increased lifespan. In light of those data, a supplement that comes to mind is dihydromyricetin, which causes the body to produce more alcohol dehydrogenase and...
  6. haidut

    Niacinamide fully reverses endotoxemia and leaky gut (from ethanol)

    The study below is a true gem due to both its broadness of impact, as well as the ease and low-cost of the therapeutic intervention it studied. Chronic endotoxemia, a cause and a result of increased gut permeability (aka "leaky gut") is now known to be a major cause of virtually all chronic...
  7. L

    Do you drink (alcohol)?

    Do you drink alcoholic beverages? If so, what do you drink? How often, and how much?
  8. FitnessMike

    How to minimize damage from alcohol?

  9. Yonebayashian

    Mulled Wine Experiment: Try for yourself!

    For years I have suffered severely from being just mentally out of it. It comes and goes and you know something is missing, especially from the moments when everything is completely fine. I felt a craving for mulled beer out of nowhere and felt a lot of mental clarity after having it. I thought...
  10. youngsinatra

    Best Supplements For Enhancing Alcohol Tolerance?

    I have a big meet-up with a dozen of old friends this weekend and we plan on partying hard. I wonder what could help with alcohol tolerance? I‘ve heard @haidut saying that aromatase inhibition can help with alcohol clearance? I personally plan on taking high dose thiamin HCL (1-2 grams) +...
  11. haidut

    Vitamin B1 can reverse heart damage/failure caused by alcoholism

    The beneficial effects of vitamin B1 (thiamine) on the nervous system have been known for a long time, and the vitamin is routinely used in hospitals around the world to treat both acute alcohol intoxication as well as the nervous system damage known as Wernicke-Korsakoff syndrome caused by...
  12. J

    The health effects of 1 - 2 drinks daily

    I was reading posts in the hair section how alcohol can help with breaking down calcification which is why homeless can have a ton of hair despite having horrible nutrition. Can having 1-2 drinks daily be healthy or beneficial? I like tequila with juice and apple ciders. I'm not drinking any...
  13. Hans

    Alcohol increases neurogenesis

    This was an interesting study that I thought was worth sharing. Many detrimental substances/compounds/neurotransmitters/hormones, are able to increase neurogenesis and are supposed to be beneficial. This study made me think of what Peat said about certain SSRI drugs increasing allopregnanolone...
  14. Lokzo

    Who Feels Euphoric The Day After Alcohol? (Alcohol Afterglow)

  15. haidut

    Alcohol Causes Liver (and Other Organ) Damage By Lowering NAD/NADH Ratio

    A neat little study, which demonstrates once again the crucial role of energy and optimal redox status in a public health issue that has now reached catastrophic proportions. Namely, alcohol-related morbidity and mortality. Those have always been an issue in any developed country but since the...
  16. haidut

    Alcohol Brain Damage Due To Iron Accumulation; Vitamin B1 To The Rescue

    Chronic alcohol abuse is highly detrimental to health and especially to the brain. Alcohol puts the body in a reductive state and depletes vitamin B1 (thiamine) stores. If the B1 deficiency becomes severe enough it manifests through what is clinically known as Wernicke-Korsakoff syndrome (WKS)...
  17. haidut

    Blocking Serotonin, Adrenaline Treats Anxiety, Brain Damage Due To Alcohol "addiction"

    Over the last 2 decades a large number of studies have come out demonstrating that the withdrawal symptoms in "addicts" are due largely due to elevated serotonin and adrenaline. As such, drugs such as cyproheptadine, clonidine, propranolol, etc have been successfully used off-label for treating...
  18. haidut

    Supplementation With (long Chain) Saturated Fats Protects Liver From Alcohol

    As many of my readers already know, there are a number of human studies, going back to at least the 1960s, demonstrating that supplementation with saturated fats (SFA) protects the liver from damage induced by alcohol. I fact, supplementation with SFA not only prevents alcohol-induced liver...
  19. haidut

    Niacinamide Can Treat Alcoholic Liver Disease

    As many forum users have probably heard on the news, alcohol abuse is now a leading cause of death in young people under 35. It is projected to soon surpass drug overdose as a cause of death in this demographic. Millennials are dying of alcohol-related liver disease at increasing rates The...
  20. haidut

    PUFA Increases Alcohol Damage By Increasing Cell Fluidity; SFA Are Protective

    Peat has written a number of times on the synergies of PUFA with ethanol and endotoxin on causing liver and systemic damage. In one of his articles he opined that in the absense of PUFA/iron ethanol would likely not cause much harm. He also wrote about the protective effects of saturated fats...
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