adrenaline

See title. Does adrenaline damage the nervous system? Thank you.

A very interesting study that highlights yet again the connection between chronic stress and ill systemic health, especially cardiovascular disease (CVD). The study demonstrates that people who had experienced a heart attack have dramatically higher higher cortisol and adrenaline/noradrenaline...

I have Unipolar Depression, Anxiety & Major Gut issues. Mirtazapine seems to have failed due to the Noradrenergic profile having a negative effect on my extremely high anxiety. Cannot even handle 15mg it seems...I want to try Seroquel, I understand it affects 5HT1A & antagonizes various 5-HT...

Hey all, I have 2 questions, the first is, does sugar raise adrenaline? And the second, what could be the cause of hypodypsia (lack of thirst)? Thank you

The timing of this study just could not have been better considering the current coronavirus epidemic. The study below demonstrates that both adrenaline and noradrenaline suppressed the immune system and both increases vulnerability to viral infection as well as increasing mortality after the...

At a first glance the study below seems rather mundane but a careful read provides some very interesting insights. The syndrome of "broken heart" is a real physiological condition that medicine has tried to deny for decades despite even assigning it its own official medical name - Takotsubo...

Over the last 2 decades a large number of studies have come out demonstrating that the withdrawal symptoms in "addicts" are due largely due to elevated serotonin and adrenaline. As such, drugs such as cyproheptadine, clonidine, propranolol, etc have been successfully used off-label for treating...

This is a remarkable study, which once again implicates extreme stress in the pathology of mental health disorders, specifically anxiety and PTSD. Just a few days ago I posted a study showing a high cortisol (C) / testosterone (T) ratio is likely causative in PTSD. People with high C/T ratio...

A Fall in Plasma Free Fatty Acid (FFA) Level Activates the Hypothalamic-Pituitary-Adrenal Axis Independent of Plasma Glucose: Evidence for Brain Sensing of Circulating FFA Endocrinology. 2012 Aug; 153(8): 3587–3592. Published online 2012 Jun 1. doi: 10.1210/en.2012-1330 PMCID: PMC3404348...

Adrenaline injections directly into the heart are the only currently approved treatment for cardiac arrest. It is considered the patient's only chance of revival and recovery. However, observational trials over the year have noticed that cardiac arrest survivors often have severe neurological...

Peat mentioned a few times that the pancreatic damage seen in type I diabetes is caused by prolonged exposure to PUFA, as unsaturated fats are toxic to the insulin-producing beta cells in that organ. Many of the cases of new onset diabetes I occur after a period of extreme exhaustion and/or...

I just posted a study in which it was shown that surgical removal of a tumor results in massive and uncontrolled formation of metastases across the entire organism. Universal Test For Cancer Progression/stage Here is the quote again, just to make the point of this thread clear. "...The...

A recent study posted on the forum found that more than 20% of newly diagnosed cancer patients experience PTSD as a result of the stress associated with the diagnosis. The fact that PTSD is still largely considered a genetically-driven disease has somehow managed to escape question about this...

This argument has flared up so many times on this forum and I doubt we have reached any agreement. I am on the side that insulin resistance and obesity are endocrine disorders. There is a group here that maintains that it is the obesity that really triggers it all. This study discusses some of...

Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans. - PubMed - NCBI Excessive or persistent proinflammatory cytokine production plays a central role in autoimmune diseases. Acute activation of the sympathetic nervous system attenuates...

The neurosteroid androsterone has some very interesting properties, among which is potent GABA agonist activity. Most GABA agonists inhibit the synthesis and/or release of epinephrine (adrenaline) and norepinephrine (noradrenaline) in various animal models and in human trials. The studies below...

Over the last few years there have been a number of studies linking SSRI use with increased risk of fracture. Subsequent studies found this link to be definitively causal - i.e. SSRI drugs cause those fractures. However, the mechanism of action was officially ascribed to the medical...

Effects of long-term treatment with the alpha 2-adrenoceptor antagonist mirtazapine on 5-HT neurotransmission. Mirtazapine (ORG 3770, Remeron) is a nonselective alpha 2-adrenoceptor antagonist with antidepressant activity in major depression. The aim of the present study was to assess, using an...

I came across this during research into increasing dopaminergic activity without also increasing adrenergic tone. Apparently, the feeling of getting drunk as well as the sedation produced by alcohol is due to the increased synthesis of adrenaline (epinephrine). Blocking that synthesis by...

Another big point in favor of salt and this time the scientists actually provide salient explanation for why the low salt diet was detrimental - i.e. it increases renin, aldosterone and adrenaline. Pretty much what Peat wrote...about 30 years before this study. It also matches well another study...