• Remembering Ray Peat Call-In Show with Georgi Dinkov

    Ray Peat Email Advice Depository

  • tca300: I understand this is off topic from what you typically teach, but I was wondering if you have run across any information or learned on your own, things that help people grieve over lost loved ones, and or fear of losing others to death? Thank you!

    Ray Peat: It activates the “helplessness” reactions in the body, stress weakening your own life, and I think it can help to get out of that if you think of your life as a continuation of theirs—the same life, though with fewer bodies.

    Rest in Paradise, Raymond Peat  October 12, 1936 - November 24 2022

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adrenaline

  1. haidut

    Lowering adrenaline as effective as opioids for severe/chronic pain

    Most of my readers know about the raging opioid abuse epidemic in Western countries. What most people do not know is that the bulk of the epidemic is not in usage of illegal opioids such as fentanyl, but in legally prescribed opioids such as methadone, oxycontin, and even morphine. There are...
    • haidut
    • Thread
    • addiction adrenaline chronic clonidine opioid pain rat park stress
    • Replies: 5
    • Forum: Scientific Studies
  2. F

    Help me plan the best post nightshift breakfast and routine for optimum sleep!

    I work a set of nights every couple of months. My shifts are usually 4 nights at a time. I’d appreciate any help in planning the best post- shift breakfast for optimum sleep. At the minute I find myself waking up after only 3 hours sleep with a racing heart and high anxiety and struggle to get...
  3. Hans

    When keto diets backfire and cause health problems

    Chronically doing a very low-carb diet can lead to problems. Obviously, not everyone suffers from them, but a relatively large percentage do. Here I talk about a few of the side effects of doing a very low carb diet...
  4. T

    Does adrenaline damage the nervous system?

    See title. Does adrenaline damage the nervous system? Thank you.
  5. haidut

    Heart attack survivors have high stress (cortisol/adrenaline) hypersensitivity, low androgens

    A very interesting study that highlights yet again the connection between chronic stress and ill systemic health, especially cardiovascular disease (CVD). The study demonstrates that people who had experienced a heart attack have dramatically higher higher cortisol and adrenaline/noradrenaline...
    • haidut
    • Thread
    • adrenaline aldosterone androgen cortisol cvd dhea heart attack stress testosterone
    • Replies: 2
    • Forum: Scientific Studies
  6. Jwicks1995

    Seroquel/Quetiapine - Cortisol/Anti-Seretonin

    I have Unipolar Depression, Anxiety & Major Gut issues. Mirtazapine seems to have failed due to the Noradrenergic profile having a negative effect on my extremely high anxiety. Cannot even handle 15mg it seems...I want to try Seroquel, I understand it affects 5HT1A & antagonizes various 5-HT...
  7. T

    Does Sugar Raise Adrenaline? And What Causes Hypodypsia (lack Of Thirst)

    Hey all, I have 2 questions, the first is, does sugar raise adrenaline? And the second, what could be the cause of hypodypsia (lack of thirst)? Thank you
  8. haidut

    Adrenaline Suppresses The Immune System And Promotes Viral Infections

    The timing of this study just could not have been better considering the current coronavirus epidemic. The study below demonstrates that both adrenaline and noradrenaline suppressed the immune system and both increases vulnerability to viral infection as well as increasing mortality after the...
    • haidut
    • Thread
    • adrenaline drive immune system infection noradrenaline promote sympathetic viral
    • Replies: 28
    • Forum: Scientific Studies
  9. haidut

    Aspirin/salt For Treating A Broken Heart, And What REALLY Causes Afib

    At a first glance the study below seems rather mundane but a careful read provides some very interesting insights. The syndrome of "broken heart" is a real physiological condition that medicine has tried to deny for decades despite even assigning it its own official medical name - Takotsubo...
    • haidut
    • Thread
    • adrenaline afib aspirin atrial fibrilation broken heart cortisol emotinal pain estrogen pain takotsubo syndrome
    • Replies: 7
    • Forum: Scientific Studies
  10. haidut

    Blocking Serotonin, Adrenaline Treats Anxiety, Brain Damage Due To Alcohol "addiction"

    Over the last 2 decades a large number of studies have come out demonstrating that the withdrawal symptoms in "addicts" are due largely due to elevated serotonin and adrenaline. As such, drugs such as cyproheptadine, clonidine, propranolol, etc have been successfully used off-label for treating...
    • haidut
    • Thread
    • adrenaline alcohol alcohol addiction brain damage cognition cure mental health pindolol serotonin treat
    • Replies: 6
    • Forum: Scientific Studies
  11. haidut

    Blocking Stress (adrenaline) Just Once Cures PTSD And Maybe Any Mental Disorder

    This is a remarkable study, which once again implicates extreme stress in the pathology of mental health disorders, specifically anxiety and PTSD. Just a few days ago I posted a study showing a high cortisol (C) / testosterone (T) ratio is likely causative in PTSD. People with high C/T ratio...
    • haidut
    • Thread
    • adrenaline anxiety beta blocker cause cure fear mental disorder mental health mental illness propranolol ptsd stress trauma treat
    • Replies: 90
    • Forum: Scientific Studies
  12. P

    Evidence For Brain Sensing Of Circulating FFA

    A Fall in Plasma Free Fatty Acid (FFA) Level Activates the Hypothalamic-Pituitary-Adrenal Axis Independent of Plasma Glucose: Evidence for Brain Sensing of Circulating FFA Endocrinology. 2012 Aug; 153(8): 3587–3592. Published online 2012 Jun 1. doi: 10.1210/en.2012-1330 PMCID: PMC3404348...
    • paymanz
    • Thread
    • acth adrenaline coconut oil corticosterone efa free fatty acids hpa oleate palmitate saturated fat stress hormones stress response
    • Replies: 0
    • Forum: Articles & Scientific Studies
  13. haidut

    Adrenaline (epinephrine) Damages The Brain

    Adrenaline injections directly into the heart are the only currently approved treatment for cardiac arrest. It is considered the patient's only chance of revival and recovery. However, observational trials over the year have noticed that cardiac arrest survivors often have severe neurological...
    • haidut
    • Thread
    • adrenaline brain cardiac arrest damage elevation epinephrine ffa neurodegeneration
    • Replies: 1
    • Forum: Scientific Studies
  14. haidut

    Anti-adrenaline Drugs Like Clonidine May Prevent Diabetes Type I

    Peat mentioned a few times that the pancreatic damage seen in type I diabetes is caused by prolonged exposure to PUFA, as unsaturated fats are toxic to the insulin-producing beta cells in that organ. Many of the cases of new onset diabetes I occur after a period of extreme exhaustion and/or...
    • haidut
    • Thread
    • adrenaline autoimmune beta cells clonidine diabetes epinephrine ffa insulin methyldopa pancreas pufa
    • Replies: 10
    • Forum: Scientific Studies
  15. haidut

    Stress (adrenaline, Noradrenaline) As The Main Driver Of Cancer Metastases

    I just posted a study in which it was shown that surgical removal of a tumor results in massive and uncontrolled formation of metastases across the entire organism. Universal Test For Cancer Progression/stage Here is the quote again, just to make the point of this thread clear. "...The...
    • haidut
    • Thread
    • adrenaline beta-blocker cancer epinephrine fatty acid oxidation growth increase lipolysis metastases noradrenaline norepinephrine stimulate stress
    • Replies: 8
    • Forum: Scientific Studies
  16. haidut

    Stress From Cancer Diagnosis Suppresses Immune System And Worsens Outcome

    A recent study posted on the forum found that more than 20% of newly diagnosed cancer patients experience PTSD as a result of the stress associated with the diagnosis. The fact that PTSD is still largely considered a genetically-driven disease has somehow managed to escape question about this...
    • haidut
    • Thread
    • adrenaline beta-blocker cancer diagnosis immune system immunosuppression outcome prognosis psychosocial stress
    • Replies: 3
    • Forum: Scientific Studies
  17. haidut

    Insulin Resistance As An Endocrine Disorder

    This argument has flared up so many times on this forum and I doubt we have reached any agreement. I am on the side that insulin resistance and obesity are endocrine disorders. There is a group here that maintains that it is the obesity that really triggers it all. This study discusses some of...
    • haidut
    • Thread
    • adrenaline cortisol diabetes disorder endocrine hpa hypothyroidism insulin resistance obesity stress
    • Replies: 22
    • Forum: Scientific Studies
  18. P

    Voluntary Activation Of The Sympathetic Nervous System And Attenuation Of The Innate Immune Response

    Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans. - PubMed - NCBI Excessive or persistent proinflammatory cytokine production plays a central role in autoimmune diseases. Acute activation of the sympathetic nervous system attenuates...
    • paymanz
    • Thread
    • adrenaline endotoxin epinehprine flu immune system inflammation meditation stress sympathetic nervous system tnf
    • Replies: 1
    • Forum: Articles & Scientific Studies
  19. haidut

    Androsterone Inhibits Catecholamines (Adrenaline / Noradrenaline)

    The neurosteroid androsterone has some very interesting properties, among which is potent GABA agonist activity. Most GABA agonists inhibit the synthesis and/or release of epinephrine (adrenaline) and norepinephrine (noradrenaline) in various animal models and in human trials. The studies below...
    • haidut
    • Thread
    • adrenaline androsterone anti-adrenaline antistress catecholamines cvd epinehprine noradrenaline norepinephrine vasorelaxation
    • Replies: 23
    • Forum: Scientific Studies
  20. haidut

    SSRI Drugs Damage Bone By Increasing Adrenaline

    Over the last few years there have been a number of studies linking SSRI use with increased risk of fracture. Subsequent studies found this link to be definitively causal - i.e. SSRI drugs cause those fractures. However, the mechanism of action was officially ascribed to the medical...
    • haidut
    • Thread
    • adrenaline beta-blocker bone loss osteoporosis reverse serotonin ssri sympathetic
    • Replies: 9
    • Forum: Scientific Studies
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