1. P

    Biotin Suppresses Food Intake

    Biotin augments acetyl CoA carboxylase 2 gene expression in the hypothalamus, leading to the suppression of food intake in mice. - PubMed - NCBI It is known that biotin prevents the development of diabetes by increasing the functions of pancreatic beta-cells and improving insulin sensitivity...
  2. haidut

    Vitamin B6 (P5P) Is An ACC Inhibitor And May Treat Obesity

    It seems vitamin B6 is especially important for the metabolism of long-chain fatty acids, which include the dreaded EPA, DHA, and arachidonic acids. The dosages of P5P that inhibited ACC-1 and ACC-2 in vitro are close to physiological and what is achievable by supplementation. Typical...