5ar

  1. fever257

    Androsterone & Sleep

    Hello all, I recently cycled Androsterone (2 drops daily) out of my regimen. I actually ran out but did not refill my supply. I did this to observe effects and see if I had brought my functioning high enough to live without it going forward. Nothing else changed in my regimen at this time...
  2. TMCMac

    Alternatives to Nicotine / Lowering DHT to 3adiol

    Anyone know of other substances or ways to lower the conversion of DHT to 3adiol other than nicotine? I suspect this is one of my issues potentially after gaining a lot of weight so looking for ways to improve this as I work on lowering body fat. Nicotine helps give me that calm masculine...
  3. W

    Progesterone inhibits 5ar?

    Whenever I took progesterone I felt anxious for several days, then I came across this article today: --- Effects of the anti-androgen finasteride on 5 alpha-reduction of androgens in the presence of progesterone in human gingival fibroblasts: modulatory actions of the alkaline phosphatase...
  4. fever257

    Next attempt to cure PFS.

    Hello, I'm inquiring about a hormonal issue engendered by an 8-9 month long course of finasteride. Around 2 years after taking finasteride, I took human chloronic gonadotropin(earlier this year) which increased my male hormones, but also massively spiked my estrogen, to the point where I have...
  5. Drareg

    5α-reductase type 2 (SRD5α2)

    Im hoping this thread can be a place to discuss this enzyme, it seems we haven’t discussed it much on here, most of the research is about inhibition, I’m curious as to how we can increase it more specifically. It converts testosterone to DHT, we have always focused on 5AR in general, we have 3...
  6. cupofcoffee

    Growth hormone and thyroid hormones stimulate liver 5 alpha-reductase

    https://pubmed.ncbi.nlm.nih.gov/2172247/ not sure if this study was posted
  7. cupofcoffee

    Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men

    https://link.springer.com/article/10.1007/s40618-021-01561-0
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