5α-dihydroprogesterone

  1. haidut

    Pregnenolone As A Treatment For Loneliness

    I touched upon this idea/topic in some of my other posts, and just like those other posts, I would like to emphasize here that I am not suggesting steroid supplementation as a substitute for social interaction. The purpose of this post if to provide some insight on the biochemical effects of...
  2. haidut

    5α-DHP - Liquid 5α-Dihydroprogesterone For Lab/R&D

    ****DISCONTINUED****DISCONTINUED****DISCONTINUED**** Replaced by allopregnanolone, which is a direct metabolite of 5α-Dihydroprogesterone (5α-DHP). https://raypeatforum.com/community/threads/allop-liquid-allopregnanolone-for-lab-r-d.41055/...
  3. haidut

    5α-Dihydroprogesterone (5α-DHP) Is Androgen/Progesterone Agonist And Pro-hormone For DHT

    If you take a look at a standard diagram of steroigenesis and metabolism you will see that the androgen DHT can be synthesized via only one route, namely DHEA->Androstenedione->Testosterone->DHT. Recently, some studies have shown that DHT can also be synthesized via an alternative pathway, still...
  4. haidut

    5α-Dihydroprogesterone (5α-DHP) - Potent Role In Neurodegenerative Conditions

    While researching saturated steroids and their effects on the brain, I noticed a number of highly promosing studies demonstrating benefit of such steroid for a variety of neurodegenerative conditions such as MS, ALS, Alzheimer, Parkinson, etc. Ray has written extensively on the topic of...
  5. haidut

    5α-Dihydroprogesterone (5α-DHP) - The Primary Progestogen Neurosteroid

    It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
  6. haidut

    5α-Dihydroprogesterone (5α-DHP) Is More Effective Than Progesterone In Lowering Prolactin

    Similar to the stud on estrogen receptor decrease, this study shows that the saturated progesterone metabolite 5α-dihydroprogesterone (5α-DHP) is more effective than progesterone at inhibiting prolactin release from the pituitary. Just as in the estrogen study, the effective doses of 5α-DHP were...
  7. haidut

    5α-Dihydroprogesterone (5α-DHP) Is More Effective Than Progesterone As Estrogen Antagonist

    The study below showed that the steroid 5α-Dihydroprogesterone (5α-DHP) is more effective that progesterone in decreasing the levels of estrogen receptor and can deliver the same result at quite low doses. The HED for 5α-DHP to achieve 75% inhibition of estrogen receptor levels were just...
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