5α-dhp

  1. haidut

    AlloP - Liquid Allopregnanolone For Lab/R&D

    Just a quick announcement that we have replaced the 5α-DHP in our store with allopregnanolone. The main reason for switching over to allopregnanolone is that we always wanted to provide that steroid right from the start, however we could not find a lab willing to synthesize it. Thus, 5α-DHP...
  2. haidut

    Pregnenolone As A Treatment For Loneliness

    I touched upon this idea/topic in some of my other posts, and just like those other posts, I would like to emphasize here that I am not suggesting steroid supplementation as a substitute for social interaction. The purpose of this post if to provide some insight on the biochemical effects of...
  3. haidut

    5α-DHP - Liquid 5α-Dihydroprogesterone For Lab/R&D

    ****DISCONTINUED****DISCONTINUED****DISCONTINUED**** Replaced by allopregnanolone, which is a direct metabolite of 5α-Dihydroprogesterone (5α-DHP). https://raypeatforum.com/community/threads/allop-liquid-allopregnanolone-for-lab-r-d.41055/...
  4. haidut

    5α-Dihydroprogesterone (5α-DHP) Is Androgen/Progesterone Agonist And Pro-hormone For DHT

    If you take a look at a standard diagram of steroigenesis and metabolism you will see that the androgen DHT can be synthesized via only one route, namely DHEA->Androstenedione->Testosterone->DHT. Recently, some studies have shown that DHT can also be synthesized via an alternative pathway, still...
  5. haidut

    5α-Dihydroprogesterone (5α-DHP) - Potent Role In Neurodegenerative Conditions

    While researching saturated steroids and their effects on the brain, I noticed a number of highly promosing studies demonstrating benefit of such steroid for a variety of neurodegenerative conditions such as MS, ALS, Alzheimer, Parkinson, etc. Ray has written extensively on the topic of...
  6. haidut

    5α-Dihydroprogesterone (5α-DHP) - The Primary Progestogen Neurosteroid

    It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
  7. haidut

    5α-Dihydroprogesterone (5α-DHP) Is More Effective Than Progesterone In Lowering Prolactin

    Similar to the stud on estrogen receptor decrease, this study shows that the saturated progesterone metabolite 5α-dihydroprogesterone (5α-DHP) is more effective than progesterone at inhibiting prolactin release from the pituitary. Just as in the estrogen study, the effective doses of 5α-DHP were...
  8. haidut

    5α-Dihydroprogesterone (5α-DHP) Is More Effective Than Progesterone As Estrogen Antagonist

    The study below showed that the steroid 5α-Dihydroprogesterone (5α-DHP) is more effective that progesterone in decreasing the levels of estrogen receptor and can deliver the same result at quite low doses. The HED for 5α-DHP to achieve 75% inhibition of estrogen receptor levels were just...
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