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11β-hydroxysteroid dehydrogenase
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11b-HSD1 inhibitors don't lower cortisol levels? increased ACTH response
a lot of people try to lower cortisol this way. But these studies with a 11b-hsd1 inhibitor given to humans shows plasma cortisol levels stay the same regardless and ACTH levels rise. (ACTH rises in response to the lower conversion of cortisone -> cortisol from the enzyme inhibition, so with...- cs3000
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- 11b-hsd1 11β-hydroxysteroid dehydrogenase 11β-hydroxysteroid dehydrogenase type 1 acth cortisol enzyme inhibition lowering
- Replies: 1
- Forum: Scientific Studies