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Quotation

Serotonin is extremely catabolic trhough its stimulation of ACTH and cortisol. That's why cyroheptadine lowers cortisol - by blocking serotonin. Anything that boosts cortisol will suppress the immune system, and as such the serotonin connection should make perfect sense. Nobody wants to admit that serotonin destroys oxidative metabolism by directly stimulating glycolysis, and suppresses the immune system (either through cortisol or directly) and thus contributes to cancer and diabetes. Peat wrote that the 3 poisonous amines ammonia, histamine, and serotonin are best kept as low as possible.