Im A Man And I Took Waaaayyyy Too Much Progesterone

Mr.Tayto

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Joined
Oct 3, 2018
Messages
97
I started taking progesterone in 2016 (for fatigue) and completely got my numbers mixed up for 2 weeks i was taking something like 80-100mg of progesterone (not under doctor supervision).
Then i found a doctor who specialises in fatigue. She put me on 20mg of progesterone a day and 65mg dhea/pregnenolone. I was naive and though more was better so would take 2 pumps of progesterone (40mg) a day every now and again. My testosterone was 440 ng/dl in 2016 (i was 26yrs old) im now 29 years old and i had my T test last week and it is 290 ng/dl. I feel completely ***t and my body is completely loosing it shape, double chin, fat at hips, soft muscle, my libido is gone and my penis has shrunk a little.
Prior to this i was always quite solid and muscley, square jaw...now i just look skinny fat.
I stopped taking progesterone in late to mid 2017 and stopped Dhea/pregnenolone in Sept 2018. Im worried ive completely ****88 myself from the progesterone..
..what can i do to get my test back up naturally?
Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf!!!!
 
Joined
Feb 25, 2018
Messages
15
I started taking progesterone in 2016 (for fatigue) and completely got my numbers mixed up for 2 weeks i was taking something like 80-100mg of progesterone (not under doctor supervision).
Then i found a doctor who specialises in fatigue. She put me on 20mg of progesterone a day and 65mg dhea/pregnenolone. I was naive and though more was better so would take 2 pumps of progesterone (40mg) a day every now and again. My testosterone was 440 ng/dl in 2016 (i was 26yrs old) im now 29 years old and i had my T test last week and it is 290 ng/dl. I feel completely ***t and my body is completely loosing it shape, double chin, fat at hips, soft muscle, my libido is gone and my penis has shrunk a little.
Prior to this i was always quite solid and muscley, square jaw...now i just look skinny fat.
I stopped taking progesterone in late to mid 2017 and stopped Dhea/pregnenolone in Sept 2018. Im worried ive completely ****88 myself from the progesterone..
..what can i do to get my test back up naturally?
Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf!!!!

I think it can be reversed. Im not an expert but im pretty sure since you are a male your body will have a natural tendency towards making testosterone. And at least progesterone's effects are mostly positive and not gland atrophying. I would consider taking thyroid if i were you if your not doing that already because thyroid hormone is probably the most important things for maintaining healthy hormone levels along with adequate nutrition and a fun/interesting life.
 

redsun

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Joined
Dec 17, 2018
Messages
3,013
I started taking progesterone in 2016 (for fatigue) and completely got my numbers mixed up for 2 weeks i was taking something like 80-100mg of progesterone (not under doctor supervision).
Then i found a doctor who specialises in fatigue. She put me on 20mg of progesterone a day and 65mg dhea/pregnenolone. I was naive and though more was better so would take 2 pumps of progesterone (40mg) a day every now and again. My testosterone was 440 ng/dl in 2016 (i was 26yrs old) im now 29 years old and i had my T test last week and it is 290 ng/dl. I feel completely ***t and my body is completely loosing it shape, double chin, fat at hips, soft muscle, my libido is gone and my penis has shrunk a little.
Prior to this i was always quite solid and muscley, square jaw...now i just look skinny fat.
I stopped taking progesterone in late to mid 2017 and stopped Dhea/pregnenolone in Sept 2018. Im worried ive completely ****88 myself from the progesterone..
..what can i do to get my test back up naturally?
Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf!!!!

Red meat, dairy, and starches for glucose will help rebuild. But, if you have gotten very overweight from progesterone use, you NEED to drop the weight first. The biggest detriment to testosterone is high body fat because it increases aromatization converting the testosterone you already make to estradiol. No amount of meat, eggs, etc will increase testosterone levels compared to getting to an appropriate body fat level first. You can eat red meat and eggs for your cut as you will still get nutrients to repair the damage you done from taking hormones that a predominantly made by and for a woman's physiology.

I mean progesterone is considered primarily a female hormone, they make much more of it because its needed for their physiology. What did you think would happen? That you could get more manly or healthier using female hormones? And at the quantity you described holy ****. Someone had to say it. And Im sure you won't be taking it anymore at all but just to be sure, avoid any kind of hormone supplements including ones that are supposed to be good for male hormones and let your body reset.
 

jzeno

Member
Joined
Nov 20, 2017
Messages
543
Don't worry. It sounds like you had a case of "well if this is good for me, more must be even better".

I don't know if it can be reversed but I would suspect it can.

What I would do is back away from the hormones for a moment. Take a deep breath and focus on the food that you are putting into your body. High carb from fruits, fruit juices and well-cooked veggies, sufficient protein from beef, eggs, milk and cheese (the ones you can stomach) and fat from saturated fats is where I would start. Avoid PUFAs and take care of your liver, which will help filtering out all the excess.

Get enough calories. Go for some exercise (15 minute walk from home and back at the very least if you're not already doing much more). Try your best to make a plan of action, execute, and then try to relax and take your mind off it.

Hopefully that helps.

All the best.
 

schultz

Member
Joined
Jul 29, 2014
Messages
2,653
Was it a topical progesterone cream? If so then you were probably not absorbing that much.

Was the DHEA also a cream? Also, was it 65mg of DHEA as well as 65mg of preg? Or was it a combination supplement? Either way, that is a lot of DHEA and if you were absorbing all of it it would be estrogen city. What kind of product was the DHEA?

I don't exactly have proof, but (based on what Ray has said) I am guessing that you were not absorbing very much progesterone at all, unless it was dissolved in DMSO or a good amount of vitamin E. What are the ingredients in this product?
 

sladerunner69

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I started taking progesterone in 2016 (for fatigue) and completely got my numbers mixed up for 2 weeks i was taking something like 80-100mg of progesterone (not under doctor supervision).
Then i found a doctor who specialises in fatigue. She put me on 20mg of progesterone a day and 65mg dhea/pregnenolone. I was naive and though more was better so would take 2 pumps of progesterone (40mg) a day every now and again. My testosterone was 440 ng/dl in 2016 (i was 26yrs old) im now 29 years old and i had my T test last week and it is 290 ng/dl. I feel completely ***t and my body is completely loosing it shape, double chin, fat at hips, soft muscle, my libido is gone and my penis has shrunk a little.
Prior to this i was always quite solid and muscley, square jaw...now i just look skinny fat.
I stopped taking progesterone in late to mid 2017 and stopped Dhea/pregnenolone in Sept 2018. Im worried ive completely ****88 myself from the progesterone..
..what can i do to get my test back up naturally?
Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf!!!!

I don't think your problems are a result of progesterone use. 80-100mg of progesterone is a large dose, but not that large. It depends what form it was in, and how you took it. I know guys who have took 200mg+ progesterone every week for long periods of time. Yes progesterone can cause libido issues because it opposes DHT and testosterone, but it can also effectively lower estrogen and promote the good metabolism. That is why many have reported that progesterone increases their libido. However, that seems to be in smaller doses.

Regardless, if it has been nearly years since you stopped taking progesterone than it is not your concern. Instead, I would look into your diet. Many people begin to suffer the woes of lowered metabolism in their late 20's, the foremost of which is weight gain and muscle loss. These things go together, because muscle tissue consumes many calories, so when you lose muscle tissue and caloric intake stays constant, you accumulate fat. Increased fat tissue will lead to loss of definition in your face. The square jaw look has mostly to do with lowering bodyfat levels. Thus, I would recommend increasing metabolism through diet, and weightlifting more.
 

Sativa

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Joined
May 17, 2018
Messages
400
I read that "Additionally, progesterone converts to estrogens, cortisol, and aldosterone."
(Context: the hormonal metabolic pathway)
So perhaps excess progesterone might lead to this happening, implying an espect of estrogen stimulation perhaps?

Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf

hmm
 

Makrosky

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Joined
Oct 5, 2014
Messages
3,982
I started taking progesterone in 2016 (for fatigue) and completely got my numbers mixed up for 2 weeks i was taking something like 80-100mg of progesterone (not under doctor supervision).
Then i found a doctor who specialises in fatigue. She put me on 20mg of progesterone a day and 65mg dhea/pregnenolone. I was naive and though more was better so would take 2 pumps of progesterone (40mg) a day every now and again. My testosterone was 440 ng/dl in 2016 (i was 26yrs old) im now 29 years old and i had my T test last week and it is 290 ng/dl. I feel completely ***t and my body is completely loosing it shape, double chin, fat at hips, soft muscle, my libido is gone and my penis has shrunk a little.
Prior to this i was always quite solid and muscley, square jaw...now i just look skinny fat.
I stopped taking progesterone in late to mid 2017 and stopped Dhea/pregnenolone in Sept 2018. Im worried ive completely ****88 myself from the progesterone..
..what can i do to get my test back up naturally?
Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf!!!!
Of course it can be reversed. Assuming you have your gonads intact (where most of the T is produced). Trans people start to revert to their original sex very quickly as soon as they stop their supplemental hormones.

I would stay away from pregnenolone also because it can be feminizing in the wrong context.

Just drop all hormones and work on improving health.

A few grams of glycine a day (very androgenic), some taurine, some fat solubles, some b vitamins, thyroid if needed... Maybe some zinc, goog calcium and magnesium, and you'll be all right.
 
OP
M

Mr.Tayto

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Joined
Oct 3, 2018
Messages
97
Wow guys thank you for your responses.
Red meat, dairy, and starches for glucose will help rebuild. But, if you have gotten very overweight from progesterone use, you NEED to drop the weight first. The biggest detriment to testosterone is high body fat because it increases aromatization converting the testosterone you already make to estradiol. No amount of meat, eggs, etc will increase testosterone levels compared to getting to an appropriate body fat level first. You can eat red meat and eggs for your cut as you will still get nutrients to repair the damage you done from taking hormones that a predominantly made by and for a woman's physiology.

I mean progesterone is considered primarily a female hormone, they make much more of it because its needed for their physiology. What did you think would happen? That you could get more manly or healthier using female hormones? And at the quantity you described holy ****. Someone had to say it. And Im sure you won't be taking it anymore at all but just to be sure, avoid any kind of hormone supplements including ones that are supposed to be good for male hormones and let your body reset.

Ya im going the gym and ny diet is on point. The best it every been. No booze at all for over 6 months now and even before that maybe once a month. No processed food. Eating Liver, seafood, milk, fruit, spinach, veg.

Finding it hard to to loose the pounds. The most ive weighed is 98kgs. Im 93kgs now before all of this i was about 86-88kgs. Im 6ft 2. I plan to get down to that again slowly, dont want to stress my body too much.

Of course it can be reversed. Assuming you have your gonads intact (where most of the T is produced). Trans people start to revert to their original sex very quickly as soon as they stop their supplemental hormones.

I would stay away from pregnenolone also because it can be feminizing in the wrong context.

Just drop all hormones and work on improving health.

A few grams of glycine a day (very androgenic), some taurine, some fat solubles, some b vitamins, thyroid if needed... Maybe some zinc, goog calcium and magnesium, and you'll be all right.

Yes ive ordered some supps on iherb.
K2, Now foods testo jack, D asparic acid, pine pollen, royal jelly, zinc polcinate, vitamin e. Hopefully that will start to push everything in the right direction...


Was it a topical progesterone cream? If so then you were probably not absorbing that much.

Was the DHEA also a cream? Also, was it 65mg of DHEA as well as 65mg of preg? Or was it a combination supplement? Either way, that is a lot of DHEA and if you were absorbing all of it it would be estrogen city. What kind of product was the DHEA?

I don't exactly have proof, but (based on what Ray has said) I am guessing that you were not absorbing very much progesterone at all, unless it was dissolved in DMSO or a good amount of vitamin E. What are the ingredients in this product?


Yes, the progestrone was a cream and fairly basic brand and the Dhea/pregnenolone was in pill form. Cannot remember excat ratio or dosage but was around 65mg mark. My doctor said my estrogen is all good so i suppose thats a start.
 

Douglas Ek

Member
Joined
Feb 8, 2017
Messages
642
I started taking progesterone in 2016 (for fatigue) and completely got my numbers mixed up for 2 weeks i was taking something like 80-100mg of progesterone (not under doctor supervision).
Then i found a doctor who specialises in fatigue. She put me on 20mg of progesterone a day and 65mg dhea/pregnenolone. I was naive and though more was better so would take 2 pumps of progesterone (40mg) a day every now and again. My testosterone was 440 ng/dl in 2016 (i was 26yrs old) im now 29 years old and i had my T test last week and it is 290 ng/dl. I feel completely ***t and my body is completely loosing it shape, double chin, fat at hips, soft muscle, my libido is gone and my penis has shrunk a little.
Prior to this i was always quite solid and muscley, square jaw...now i just look skinny fat.
I stopped taking progesterone in late to mid 2017 and stopped Dhea/pregnenolone in Sept 2018. Im worried ive completely ****88 myself from the progesterone..
..what can i do to get my test back up naturally?
Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf!!!!

Of course it can be reversed. It can take some time. I tested 114 in testosterone at one point. 2 months later it was 624. And 1,5 year later it was 923. I would recommend anabolicmen.com read about the nutrition parts. Very good advice and actually does work. Supplements would be the last piece of the puzzle.
Nutrition

Very simplified version of this would be as follows:

  • Consume foods that are rich in essential pro-testosterone nutrients.
  • Avoid foods that have that suppress testosterone (estrogenic, goitrogenic, etc).
  • Consume adequate calories. Starvation downregulates androgen production.
  • Stay close to macronutrient ratios of 25% protein, 25% fat, 50% carbohydrate.
  • Limit your intake of proven test suppressants; PUFA, trans-fats, and processed grain.
  • Include proven androgenic foods in your diet; eggs, coconut oil, root-vegetables, fruits...
Carbohydrates and Testosterone: Non-Essential but Still Important

Fats and Testosterone: Dietary Fat, PUFA, & Androgens

30 Foods that Boost Testosterone Levels Naturally

These articles are great and explain some basic stuff how the body works. Regarding diet.
Its better go get the picture and understand how hormones interact. Good thyroid is also essential to good T production. Have you tested this? Have you tested your estrogen? Have you tested cortisol? Have you tested prolactin. These hormones usually play the role as of why someone has low testosterone. High cortisol could be sign of stress, over-exercising, eating to little food/calories (this is a stress to the body). High estrogen could mean you have to much body fat (high PUFA) and inflammation. Try to lose weight take inflammatory drugs like aspirin, vitamin E and other estrogen inhibitors. High prolactin usually vitamin D, calcium deficiency or dopamine deficiency due to high serotonin or something like that. There’s many reasons. Usually addressing lifestyle factors, diet, exercise and taking some supplements are enough to switch the whole being into a completely different direction. But I would advice against taking big or more than the recommended dose of any supplement without having more bloodwork done. Other wise you are shooting in the dark just guessing. And just as progesterone did you can end up doing more harm than good.
 

schultz

Member
Joined
Jul 29, 2014
Messages
2,653
Trans fat isn't necessarily bad. Ray eats hydrogenated coconut oil which adds trans fat.

Completely hydrogenated oils will not contain transfat. Partially hydrogenated oil will though. I would imagine coconut oil is a very easy oil to hydrogenate because it is already so saturated, so I doubt there is much trans fat, if any, after hydrogenation.

CLA is a transfat in ruminant animals. It is from partial hydrogenation in the rumen.
 

schultz

Member
Joined
Jul 29, 2014
Messages
2,653
I did not know that. Why is this?

The hydrogenation completely saturates the fat. Trans fat is sort of in-between being unsaturated and being saturated. So if you partially hydrogenated something like sunflower oil which has a lot of unsaturated fat, you'll be left with a bunch of trans fat since the hydrogenation process wasn't completed. It is not practical for food manufacturers to completely hydrogenate something like soy or sunflower oil because the melting point becomes really high, like 150 degrees F for soybean oil. So with partial hydrogenation they can get the fat to the melting point that they think the consumer would like. I imagine fully hydrogenated soybean oil would be like eating wax.

I was just reading the wiki on trans fat and noticed some interesting things...

"Trans fats levels can be reduced or eliminated using saturated fats such as lard, palm oil, or fully hydrogenated fats, or by using interesterified fat. Other alternative formulations can also allow unsaturated fats to be used to replace saturated or partially hydrogenated fats. Hydrogenated oil is not a synonym for trans fat: complete hydrogenation removes all unsaturated fats."

I was wondering how they could make modern margarines without trans fat, and I guess interesterified fat is the answer. Also, they call lard a saturated fat, which really bothers me when they do that in studies.

The elaidic acid page says this...

"Elaidic acid occurs naturally in small amounts in caprine and bovine milk (very roughly 0.1% of the fatty acids)[2] and in some meats.[3] It also comprises 2.50% of the fats from the fruit of the durian species Durio graveolens."

Durian fruit has 2.5% trans fat? That's so interesting!
 
OP
M

Mr.Tayto

Member
Joined
Oct 3, 2018
Messages
97
Of course it can be reversed. It can take some time. I tested 114 in testosterone at one point. 2 months later it was 624. And 1,5 year later it was 923. I would recommend anabolicmen.com read about the nutrition parts. Very good advice and actually does work. Supplements would be the last piece of the puzzle.
Nutrition

Very simplified version of this would be as follows:

  • Consume foods that are rich in essential pro-testosterone nutrients.
  • Avoid foods that have that suppress testosterone (estrogenic, goitrogenic, etc).
  • Consume adequate calories. Starvation downregulates androgen production.
  • Stay close to macronutrient ratios of 25% protein, 25% fat, 50% carbohydrate.
  • Limit your intake of proven test suppressants; PUFA, trans-fats, and processed grain.
  • Include proven androgenic foods in your diet; eggs, coconut oil, root-vegetables, fruits...
Carbohydrates and Testosterone: Non-Essential but Still Important

Fats and Testosterone: Dietary Fat, PUFA, & Androgens

30 Foods that Boost Testosterone Levels Naturally

These articles are great and explain some basic stuff how the body works. Regarding diet.
Its better go get the picture and understand how hormones interact. Good thyroid is also essential to good T production. Have you tested this? Have you tested your estrogen? Have you tested cortisol? Have you tested prolactin. These hormones usually play the role as of why someone has low testosterone. High cortisol could be sign of stress, over-exercising, eating to little food/calories (this is a stress to the body). High estrogen could mean you have to much body fat (high PUFA) and inflammation. Try to lose weight take inflammatory drugs like aspirin, vitamin E and other estrogen inhibitors. High prolactin usually vitamin D, calcium deficiency or dopamine deficiency due to high serotonin or something like that. There’s many reasons. Usually addressing lifestyle factors, diet, exercise and taking some supplements are enough to switch the whole being into a completely different direction. But I would advice against taking big or more than the recommended dose of any supplement without having more bloodwork done. Other wise you are shooting in the dark just guessing. And just as progesterone did you can end up doing more harm than good.

Sorry for late reply, i have been busy with work.

My thyroid is good but here are the results
Tsh 2.17 mu/l
T4 12 pmol/l
T3 4.5 pmol/l
Tpo ab 12.9 iu/ml
Tg ab <10 iu/ml

Prolactin 282 mIU/l , this was 113 back in 2013. I took some cyproheptadine last year and really didnt agree with me. I feel as if it raised my prolactin and reduced dopamine as this is when i started getting extra depressed. I also feel it lowered my test around this time too.

My cortisol has been tested recently, a 24hr saliva test. The results were ok except my cortisol was 20 nmol/l at midday when the range is 2-11 nmol/l.

Oestradiol 90 pmol/l.
This number has been better before, at 70pmol/l, it has started to creep up at bit recently. I have Vitamin E on hand to keep it down.


I went on to the Anabolic men website and read a ***t ton of articles and purchased some Suma root and Butea Superba aswell. Going to cycle these as i want to gentley shift my back to a more anabolic direction.

Also going to buy some tinned liver paste that i can eat at work while on the go and also cinnamon seems to be promising aswell so going to gave that with Milk quite often too.
 

Xemnoraq

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Joined
Oct 3, 2016
Messages
264
Age
27
I started taking progesterone in 2016 (for fatigue) and completely got my numbers mixed up for 2 weeks i was taking something like 80-100mg of progesterone (not under doctor supervision).
Then i found a doctor who specialises in fatigue. She put me on 20mg of progesterone a day and 65mg dhea/pregnenolone. I was naive and though more was better so would take 2 pumps of progesterone (40mg) a day every now and again. My testosterone was 440 ng/dl in 2016 (i was 26yrs old) im now 29 years old and i had my T test last week and it is 290 ng/dl. I feel completely ***t and my body is completely loosing it shape, double chin, fat at hips, soft muscle, my libido is gone and my penis has shrunk a little.
Prior to this i was always quite solid and muscley, square jaw...now i just look skinny fat.
I stopped taking progesterone in late to mid 2017 and stopped Dhea/pregnenolone in Sept 2018. Im worried ive completely ****88 myself from the progesterone..
..what can i do to get my test back up naturally?
Please tell me this can be reversed?
Please help!!!

I only found out recently progesterone is what trans use to lower their T....Wtf!!!!
If i had to guess what your issue is here based on my (unprofessional opinion) i would guess that it maybe wasnt the progesterone causing your issues, but the DHEA, according to studies and what Peat states about DHEA, 65mg is a massive dose, waaay more than needed, and it has been stated a few times that anything beyond 15mg-25mg of DHEA will convert into estrogen, so 65mg is a whopping dose, Peat has even said that a safe amount of DHEA sometimes 2mg-3mg is all thats needed, personally i would try either reducing the DHEA or removing it from the equation and see if anything changes for you? Since progesterone has anti-estrogenic effects, to me it would seem more likely that progesterone would slim out the face and the entire body because estrogen causes water retention and bloating, and so since progesterone cannot be converted to estrogen based on what i,ve read, im strongly convinced the dose of DHEA is 12x more than what it should be,

But thats just my opinion i could be wrong, you can always give it a shot by removing or lowering DHEA from the equation and see where that goes, also taking pregnenolone will convert into some DHEA likely downstream, so i would say it's even questionable whether you would need to take DHEA at all, if the dosage of pregnenolone is high,

Again im no expert though im just sharing things i've heard based on my own research, and Ray, and the forum here,

Best of luck mate!

Also- i noticed some similar issues as you, and i think i had also been dosing DHEA too high, i have always been like 6-8% bodyfat my whole life, since adding DHEA ive gained noticible bodyfat, it could be other things like as a result of lowered cortisol, meaning its easier for me to put on weight in a healthy way (being that i was too skinny before from stress)

Not sure though man but hopefully that helps!
 

Waynish

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Joined
Oct 11, 2016
Messages
2,206
Can you link to the progesterone product you used? Many people have said it increases their anabolism, which would improve shape.
 
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Mr.Tayto

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Joined
Oct 3, 2018
Messages
97
Im back again and i need so serious help. This whole this is effecting my mental health. I dont recognise the person in the mirror any more and havent for a long time. The progesterone/pregnenolone/dhea has change my facial features so much its causing me major depression....

My head is fried. Ive had to takeca month off work to clear my head.

I have a question....
Since the above hormones changed my facial features so much, does anybody here think that if took TRT it would help reverse the changes some what is know this would take time but i be willing to do it if i knew i could get a result.

My total T at the moment is 26, its pretty healthy but i havent seen my face change to becoming more manly at all really....

I researched the whole internet but no straight answers surely someone here would know of in theory know...
 

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