How Can I UNDERMETHYLATE Myself?

[Lokzo]

I have been playing around with excessive betaine (From beetroot powder), and I have other choline sources in my diet. Right now I display the exact symptoms of being overmethylated.

Is there a supplement/vitamin that is able to quickly reduce this overmethylation?

Thanks

 

[High_Prob]

I have been playing around with excessive betaine (From beetroot powder), and I have other choline sources in my diet. Right now I display the exact symptoms of being overmethylated.

Is there a supplement/vitamin that is able to quickly reduce this overmethylation?

Thanks

Niacinamide/Niacin

 

[Lokzo]

Niacinamide/Niacin

I had a feeling this was going to be the one.
I just had 20mg pure Niacin, not niacinamide, orally. Will see how this goes.

 

[Lokzo]

Niacinamide/Niacin

Okay, all I can say is what a massive relief!!! Thankyou for that. Feeling way less on edge/anxious. Overmethylation is a terrible feeling.

 

[Lokzo]

Apart from Niacin, what are some other ways to promote UNDER-methylation? I always respond extremely well to L-Histidine.

 

[lampofred]

Increase CO2 and make gelatin a major source of your daily protein (so you can avoid methionine, which is what donates the methyl groups to cause methylation).

 

[paymanz]

We talking about dna methylation ,right?!

Lidocaine also de methylate dna

Lidocaine Demethylates DNA

But i dont have any idea about dosage, and you must be careful doing this.

 

[ddjd]

I have been playing around with excessive betaine (From beetroot powder), and I have other choline sources in my diet. Right now I display the exact symptoms of being overmethylated.

Is there a supplement/vitamin that is able to quickly reduce this overmethylation?

Thanks

Regular niacin

 

[ddjd]

Niacinamide/Niacin

Only Niacin works. Not niacinamide

 

[High_Prob]

Only Niacin works. Not niacinamide

I thought that the methyl groups were used when Niacin breaks down to Nicotinamide (Niacinamide) to create Methylnicotinamide so that it can then be excreted...

 

[ddjd]

I thought that the methyl groups were used when Niacin breaks down to Nicotinamide (Niacinamide) to create Methylnicotinamide so that it can then be excreted...

I've tried both. Only Niacin works

 

[Lokzo]

Yeah, the Niacin has worked marvelously for me. I can now use the Beetroot Powder before my workout, without feeling highly anxious/overmethylated. I am also stacking it with L-histidine (200mg), and feeling super alert, but calm at the same time.

 

[achar45]

Folic and Folinic Acid also lower methylation.

 

[ddjd]

Yeah, the Niacin has worked marvelously for me. I can now use the Beetroot Powder before my workout, without feeling highly anxious/overmethylated. I am also stacking it with L-histidine (200mg), and feeling super alert, but calm at the same time.

did you ever test niacinamide to reduce methylation?

 

[Lokzo]

did you ever test niacinamide to reduce methylation?

I did try it, but it doesn't yield the same feeling that Niacin does.

 

[moriwatzi]

Folic and Folinic Acid also lower methylation.

This.

Niacin always work though. Sometimes you just have to get up to few grams a day for a little while.

 

[zewe]

Only Niacin works. Not niacinamide

Correct!

 

[ddjd]

Correct!

Apparantly in another group someone posted saying Chris Masterjohn just did an article claiming Niacinamide also works. She didnt post a link though!

 

[zewe]

Apparantly in another group someone posted saying Chris Masterjohn just did an article claiming Niacinamide also works. She didnt post a link though!

@Joeyd , Chris Masterjohn is comparatively new on the methylation bandwagon.

I think pioneers such as Dr. Lynch use niacin due to its quick effect. Which would be most welcomed when one is dealing with head & neck pain, intense anxiety and possible paranoia symptoms of overmethlyation.

The niacin flush [vasodilation] happens a few minutes after it's taken. Niacin increases blood flow, hence a rapid delivery of the desired effect.

 

[ddjd]

I have been playing around with excessive betaine (From beetroot powder), and I have other choline sources in my diet. Right now I display the exact symptoms of being overmethylated.

Is there a supplement/vitamin that is able to quickly reduce this overmethylation?

Thanks

out of interest why were you experimenting with betaine? and why beetroot powder and not TMG?