dementia

  1. haidut

    STUDY: high serotonin linked to dementia; MEDIA: low serotonin linked to dementia

    Once again, a level of misreporting that I am much more included to ascribe to malice than incompetence simply because most of the popular press outlets covering a specific scientific study get the study authors to proof-read the press article before publishing. So, for patently false press...
  2. haidut

    PARADOX: Cortisol promotes inflammation, drives Alzheimer's Disease (AD)

    It looks like serotonin (5-HT), commonly known as the "happy hormone" has a serious competitor for the title of the most grossly mischaracterized substance in medicine. That serious competitor is cortisol, in both its synthetic and bioidentical forms, commonly known as the "master of...
  3. M

    Elderly mother in law hallucinating: is it dementia, or adverse drug reaction to antihistamines, alendronic acid??

    Hi, this is complicated so I'm going to try to bottom line it as much as possible but give all the important details to describe this situation. So, my husband and I live with his parents, and my elderly MIL has been showing some mild symptoms of what my FIL is convinced are early signs of...
  4. haidut

    Human trial - niacinamide may treat Alzheimer Disease (AD)

    One of my first posts on the topic of bioenergetics - more than a decade ago - was in regards to a promising animal study with the human-equivalent dose (HED) of 30mg/kg niacinamide (NAM) daily showing robust effects on that animal species' model of AD. The authors of the animal study followed...
  5. haidut

    High serotonin linked to poor aging trajectory (brain atrophy and depression)

    This is one of the studies that Big Pharma will probably spend a lot of money on trying to get retracted. It directly demonstrates that elevated serotonin (5-HT) in the brain drives brain atrophy and depression. Both the rates and severity of these conditions increase with aging and the study...
  6. haidut

    Serotonin (5-HT) may drive both schizophrenia and Alzheimer Disease (AD)

    Unbeknownst to most people, psychiatry has started to make a quiet "paradigm shift" in regards to psychotic conditions such as schizophrenia. Namely, after claiming for decades that psychotic states are caused by excessive dopamine levels/activity, psychiatry has now quietly change the official...
  7. haidut

    Endotoxin, cold, flue increase risk of dementia

    I am posting this study not so much because of the link between chronic low-grade inflammation and neurological conditions it demonstrates. That link is by now well-known even in mainstream medical circles. The main reason this study/article caught by eye is that the experiment mimicked the...
  8. cs3000

    Cerebral vitamin B5 deficiency (pantothenic acid) as a potentially reversible cause of neurodegeneration and dementia in Alzheimers HD PD [myelin]

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630497/ b5 plays a role in helping age related cognitive decline , used for myelin aka. the sheath around nerves that enables electrical signals to travel well , along with cellular ATP from oxidative phosphorylation Vitamin B5 (d-pantothenic...
  9. haidut

    Vitamin D may prevent dementia / Alzheimer's Disease (AD)

    The study is observational and does not really include information on specific dosing, but it was written in a way that suggests any exposure to vitamin D over a year was linked to significantly lower risk of both getting dementia/AD and/or dying from it over the next 5 years. Considering the...
  10. AlphaCog

    Chris Hemsworth's APOE4 Alzheimer's Gene — The Thor actor recently learned about his genetic predisposition.

    by Michele R. Berman, MD December 1, 2022 Australian actor Chris Hemsworth, best known for his role as Thor in the Marvel Universe, revealed he is at increased risk of developing Alzheimer's disease due to a genetic predisposition. Hemsworth learned this while filming a new National Geographic...
  11. haidut

    Endotoxin (LPS) causes Alzheimer Disease (AD)

    I have made posts on this topic in the past, but it seems this most recent study directly states that endotoxin/LPS is a major cause of AD. All other studies have been either animal models or did not directly implicate LPS. The study below claims to be the first that integrates all available...
  12. haidut

    BREAKING: Seminal study, core of the amyloid-Alzheimer theory, was FABRICATED!

    It rarely gets any more damning for a scientific field than what was just announced today. Namely, the study considered the most important/influential in maintaining scientific support for the central dogma of dementia research - the beta-amyloid hypothesis of Alzheimer Disease (AD) - was not...
  13. haidut

    Lifestyle, not age, rules cognitive function...

    ...whether you are 18 or 80. Yes, I know it is hard to believe this statement but that is the conclusion of the study after examining the link between lifestyle (and environment) and cognitive function in a group of people with ages spanning the 18-89 years interval. The conclusion of the study...
  14. haidut

    Low-dose aspirin may prevent most dementias (even Alzheimer's)

    Over the last couple of months, a few studies came out arguing (again) that aspirin is not worth the risk and that people should stop taking it. It seems that Big Pharma has a schedule of pumping propaganda out every year or so against the main "threats" to its dominance - aspirin, vitamin D...
  15. haidut

    Vitamin B1 as a potential treatment for Alzheimer's Disease (AD)

    After decades of denial that AD is a metabolic condition, Big Pharma and Big Govt, are silently doing an 180-degree turn by secretly funding university clinical trials for metabolic interventions in that disease. The study below will evaluate the effects of benfotiamine - a lipophilic analog of...
  16. haidut

    Vitamin D Deficiency Can Lead to Dementia And Stroke

    Despite this being an observational study, the analysis for extraneous factors has been strong enough that the authors believe the link between vitamin D deficiency and dementia/stroke is causal. As the study itself says, almost 20% of dementia/stroke cases could be prevented by simply...
  17. haidut

    Allopregnanolone found safe, may slow brain atrophy from Alzheimer's

    A great new study, which is one of the very few to examine the safety and effectiveness of allopregnanolone in humans. The trial was conducted in patients with Alzheimer Disease (AD) and aimed to establish the safety of various doses of once-weekly allopregnanolone administration, as well as any...
  18. haidut

    Blocking endotoxin may reverse cognitive decline of aging

    Another study implicating endotoxin (LPS) and its associated receptor (TLR4) in a phenotype of aging considered "normal" by mainstream medicine, though it almost universally progresses into dementia territory with advancing age, to the point where 90%+ of people over 85 have at least moderate...
  19. haidut

    Alzheimer's Severity Tied to Longer Estrogen Exposure in Women

    A neat study, which somehow managed to slip through my "radar" when it was first published the middle of last (2021) year. The study is pretty straighforward in its claim that longer exposure to endogenous estrogen was associated with exacerbated/higher biomarkers of Alzheimer disease (AD), as...
  20. haidut

    High (extracellular) serotonin causes Alzheimer's and depression

    The utter corruption of "journalism" is once again on full display in MSM. The actual scientific study is very clear in its statements/conclusions that a decrease in the levels of serotonin transporter (5-HTT) led to accumulation of beta-amyloid and onset of depression. Lower levels of 5-HTT -...
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