aging

  1. haidut

    LipOdd - Liquid Product With Odd-Chain Saturated Fats (SFA)

    More than a decade ago, when I was just beginning my exploration of bioenergetics, one of the first indications that Ray's writings were onto something when it came to SFA vs. PUFA was the fact that while mainstream medicine ruthlessly bashed SFA in general and promoted PUFA, virtually very...
  2. haidut

    How adrenochrome works - it is a potent oxidizer/quinone and serotonin antagonist

    As most of my readers know, the topic of adrenochrome is perhaps one of the most controversial in both politics and medicine, due to its purported harvesting from children and usage for anti-aging purposes, as well as due to its purported role in causing schizophrenia and a number of other...
  3. haidut

    Increasing serotonin (5-HT) breakdown delays/prevents aging

    The naked mole rat (NMR) is one of the most fascinating species. Despite being a humble rodent, much smaller than a regular house/city rat, the NMR has an exceptionally long life-span of 35+ years (compared to 2-3 years for the common rat) and on top of that is remarkably resistant to the...
  4. haidut

    Blocking prostaglandins restores (glucose) metabolism, reverses brain aging

    It is rare to find a study like the one below that combines so many crucial topics into a unified message. Namely, the role of energy in aging and disease, the role of oxidative glucose metabolism in aging and health, the pathological role of PUFA as a negative (glucose) metabolic regulator and...
  5. C

    I've NEVER Seen "Coconut" Associated With Longevity or Centenarians

    I just realized that after reading about the diets of exceptionally healthy people in their 90s and older and I've never seen the word coconut once. I've seen they eat chocolate, bacon, eggs, olive oil, milk but never seen the word "coconut" in the context of a supercentenarian or really anyone...
  6. C

    Is It Worth Decreasing PUFA From 2 Grams to 1 Over Lifetime? Would It Matter?

    Is it worth switching from lentils to adzuki beans or coconut oil to MCT for example? Would there be any actual benefit of reducing PUFA intake by 50% but by only 1gram over 90 years?
  7. C

    Have Filters Changed The Game? Who Looks Good? What now?

    Can you trust your eyes anymore on who's doing things right? I would look for long term vegans, fruitarians, keto etc. to see how they're holding up in their video interviews. Photos have been useless for decades but videos still told the truth until recently. I've noticed a lot of older...
  8. cs3000

    Hesperidin in 1 glass of orange juice reverses sarcopenia, lowers inflammation, & restores IGF-1 (age related muscle loss)

    Cool research as OJ is commonly accessible, nice effect on restoring igf-1 lowering inflammation and reversing muscle loss in aging (and probably myelin repair for brain function too), and its effect is in already aged mice so can be taken later in life for this health boost 1 250ml glass of...
  9. haidut

    Restoring mitochondrial function reverses aging in blood/immune cells

    The number of studies focusing on bioenergetics as a reliable method for delaying (or even reversing) aging continues to rapidly grow. A few years ago, an in-vivo study with humans demonstrated that human immune system aging can be reversed by a combination of DHEA and a few other, less...
  10. TruffleGnocchi

    DHEA levels in young children? And how to prevent it's conversion?

    There are papers talking about DHEA decline and supplementation could resolve a lot of problems related to aging. I see some sources say DHEA levels are low or significantly lower in childhood than in teens or young adults. Is this really the hormone of such importance if this is true? When I...
  11. A

    The Feeling of Hunger Itself May Slow Aging

    https://scitechdaily.com/the-feeling-of-hunger-itself-may-slow-aging Researchers at the University of Michigan have found that the perception of hunger alone, as opposed to actual food restriction, may slow aging. Their experiments with flies demonstrated that inducing hunger, either through...
  12. HeartGold

    Sun damage

    Hi! Is it possible to heal this type of sun damage? Does it look dehydrated? I’m only 28 and had great skin until I was 26. My guess is that it’s from a combination of sun, stress and pollution. I tried niaciamide (orally), thiamine(orally), tallow and progesterone cream but not much helped...
  13. Sapien

    Ray peat wrong about casein having less inflamitory amino acids than whey?

    I often heard peat say that casein is lower in the inflammatory amino acids (methionine, cysteine, tryptophan) than whey, and I was curious to know how much of a difference there was. After some searching, I kept finding (looked at 5+ analysis) that they actually have very similar amounts of...
  14. TruffleGnocchi

    Bioelectricity resource collection, Michael Levin specifically (videos, websites, statements, and other)

    A collection of videos of Michael Levin, his website, some of the statements he made or takeaways, off the top of my head. Bioelectricity according to Michael Levin and his research team: (he did say this was studied before him, he doesn't claim it as his own afaik) - Genes do not code what...
  15. JamesGatz

    Let's be honest - AGING ISN'T REAL

    Trees don't Age Alligators don't Age (They also always regrow teeth and never stop growing after Puberty) Amish men easily make it past 100 (and their diet/lifestyle COULD BE WAY BETTER) Native American men easily made it to 140 years old, smoking Tobacco EVERY DAY Methesulah lived to the...
  16. haidut

    Aspirin / eugenol can remove lipofuscin from cells

    One of the visible hallmarks of aging is the accumulation of so-called "age pigment" or "aging spots", commonly known in scientific circles as lipofuscin. The latter is a complex mix of peroxidized polyunsaturated fats (PUFA) and various metals (especially iron) that accumulates in cells with...
  17. haidut

    Restoring mitochondrial function may be sufficient to reverse aging

    The findings of the study may not sound very novel to my readers, however please keep in mind that the vast majority of anti-aging studies so far have only looked at slowing (not even stopping) aging. Actually reversing aging is the Holy Grail of gerontology, and to date very few studies have...
  18. haidut

    The "cancer metabolism" drives aging in humans

    A truly monumental study, as it is perhaps the first one to demonstrate that "aging" in human cells is entirely under metabolic control. What can I say - Ray Peat right again! Unfortunately, the way the actual study has been worded has been, once again, criminally mis-represented by mainstream...
  19. C

    Aging Of A 53 YO Male After 25yrs of Dutasteride 35yrs Oral Steroids + No Testosterone Or DHT

    On top of suppressing his natural testosterone production to nothing until age 51 by taking oral steroids, he suppressed his dht to about zero by taking a full dose of dutasteride. He added 125mg of testosterone at age 51 and used to take aromatase inhibitors when he was taking growth hormone...
  20. cs3000

    Hesperetin restores youth in old rats - enhances lifespan ~8% up to ~14% when given late, restores mitochondria & metabolism, reverses heart damage

    Posting this part from a thread i wrote on Hesperidins beneficial effects on toxic metal protection, diabetes, wound healing etc Great study on the life promoting effects of hesperitin (the derivative of hesperidin found in orange juice): *Reverses effects of aging / restores youth...
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